Dataset: Vastus lateralis biopsies from healthy and COPD patients before and after 8 weeks of exercise training

Study the training exercise effects in chronic obstructive pulmonary disease (COPD) patients and aged-matched healthy individuals....

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Study the training exercise effects in chronic obstructive pulmonary disease (COPD) patients and aged-matched healthy individuals. Skeletal muscle biopsies from 9 stable COPD patients with normal fat free mass index (FFMI, 21Kg/m2) (COPDN), 6 COPD patients with low FFMI (16Kg/m2) (COPL), and 12 healthy sedentary subjects (FFMI 21Kg/m2) before and after 8 weeks of a supervised endurance exercise program were analyzed. Samples were collected from open biopsies from the musculus vastus lateralis of COPD patients and healthy individuals before and after 8 weeks of exercise training. Constant-work rate exercise at 70% of pre-training Watts peak (Wpeak) (CardiO2 cycle Medical Graphics Corporation, USA) was carried out before and after 8 weeks of supervised interval training with a cycloergometer until pre-training endurance time exhaustion. Measurements before and after training were obtained at isowork-rate and iso-time.

Species:: human
Samples:: 54
Source:: E-GEOD-27536
PubMed:: 21909251
Updated:: Dec.12, 2014
Registered:: Jul.11, 2014

Factors: (via ArrayExpress)

Sample	DISEASE STATE	BMI	INDIVIDUAL	EXERCISE STATE
GSM680082	Chronic Obstructive Pulmonary Disease (COPD)	low	42	trained
GSM68008	Chronic Obstructive Pulmonary Disease (COPD)	low	41	trained
GSM680080	Chronic Obstructive Pulmonary Disease (COPD)	low	39	trained
GSM680079	Chronic Obstructive Pulmonary Disease (COPD)	low	38	trained
GSM680078	Chronic Obstructive Pulmonary Disease (COPD)	low	37	trained
GSM680077	Chronic Obstructive Pulmonary Disease (COPD)	low	36	trained
GSM680076	Chronic Obstructive Pulmonary Disease (COPD)	low	42	sedentary
GSM680075	Chronic Obstructive Pulmonary Disease (COPD)	low	41	sedentary
GSM680074	Chronic Obstructive Pulmonary Disease (COPD)	low	39	sedentary
GSM680073	Chronic Obstructive Pulmonary Disease (COPD)	low	38	sedentary
GSM680072	Chronic Obstructive Pulmonary Disease (COPD)	low	37	sedentary
GSM68007	Chronic Obstructive Pulmonary Disease (COPD)	low	36	sedentary
GSM680070	Chronic Obstructive Pulmonary Disease (COPD)	normal	34	trained
GSM680069	Chronic Obstructive Pulmonary Disease (COPD)	normal	30	trained
GSM680068	Chronic Obstructive Pulmonary Disease (COPD)	normal	27	trained
GSM680067	Chronic Obstructive Pulmonary Disease (COPD)	normal	25	trained
GSM680066	Chronic Obstructive Pulmonary Disease (COPD)	normal	24	trained
GSM680065	Chronic Obstructive Pulmonary Disease (COPD)	normal	22	trained
GSM680064	Chronic Obstructive Pulmonary Disease (COPD)	normal	20	trained
GSM680063	Chronic Obstructive Pulmonary Disease (COPD)	normal	18	trained
GSM680062	Chronic Obstructive Pulmonary Disease (COPD)	normal	17	trained
GSM68006	Chronic Obstructive Pulmonary Disease (COPD)	normal	34	sedentary
GSM680060	Chronic Obstructive Pulmonary Disease (COPD)	normal	30	sedentary
GSM680059	Chronic Obstructive Pulmonary Disease (COPD)	normal	27	sedentary
GSM680058	Chronic Obstructive Pulmonary Disease (COPD)	normal	25	sedentary
GSM680057	Chronic Obstructive Pulmonary Disease (COPD)	normal	24	sedentary
GSM680056	Chronic Obstructive Pulmonary Disease (COPD)	normal	22	sedentary
GSM680055	Chronic Obstructive Pulmonary Disease (COPD)	normal	20	sedentary
GSM680054	Chronic Obstructive Pulmonary Disease (COPD)	normal	18	sedentary
GSM680053	Chronic Obstructive Pulmonary Disease (COPD)	normal	17	sedentary
GSM680052	healthy	normal	9	trained
GSM68005	healthy	normal	8	trained
GSM680050	healthy	normal	7	trained
GSM680049	healthy	normal	5	trained
GSM680048	healthy	normal	4	trained
GSM680047	healthy	normal	2	trained
GSM680046	healthy	normal	15	trained
GSM680045	healthy	normal	13	trained
GSM680044	healthy	normal	12	trained
GSM680043	healthy	normal	11	trained
GSM680042	healthy	normal	10	trained
GSM68004	healthy	normal	1	trained
GSM680040	healthy	normal	9	sedentary
GSM680039	healthy	normal	8	sedentary
GSM680038	healthy	normal	7	sedentary
GSM680037	healthy	normal	5	sedentary
GSM680036	healthy	normal	4	sedentary
GSM680035	healthy	normal	2	sedentary
GSM680034	healthy	normal	15	sedentary
GSM680033	healthy	normal	13	sedentary
GSM680032	healthy	normal	12	sedentary
GSM68003	healthy	normal	11	sedentary
GSM680030	healthy	normal	10	sedentary
GSM680029	healthy	normal	1	sedentary