Dataset: Vastus lateralis biopsies from healthy and COPD patients before and after 8 weeks of exercise training

Study the training exercise effects in chronic obstructive pulmonary disease (COPD) patients and aged-matched healthy individuals....

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Study the training exercise effects in chronic obstructive pulmonary disease (COPD) patients and aged-matched healthy individuals. Skeletal muscle biopsies from 9 stable COPD patients with normal fat free mass index (FFMI, 21Kg/m2) (COPDN), 6 COPD patients with low FFMI (16Kg/m2) (COPL), and 12 healthy sedentary subjects (FFMI 21Kg/m2) before and after 8 weeks of a supervised endurance exercise program were analyzed. Samples were collected from open biopsies from the musculus vastus lateralis of COPD patients and healthy individuals before and after 8 weeks of exercise training. Constant-work rate exercise at 70% of pre-training Watts peak (Wpeak) (CardiO2 cycle Medical Graphics Corporation, USA) was carried out before and after 8 weeks of supervised interval training with a cycloergometer until pre-training endurance time exhaustion. Measurements before and after training were obtained at isowork-rate and iso-time.

Species:: human
Samples:: 54
Source:: E-GEOD-27536
PubMed:: 21909251
Updated:: Dec.12, 2014
Registered:: Jul.11, 2014

Factors: (via ArrayExpress)

Sample	DISEASE STATE	INDIVIDUAL	BMI	EXERCISE STATE
GSM680082	Chronic Obstructive Pulmonary Disease (COPD)	42	low	trained
GSM68008	Chronic Obstructive Pulmonary Disease (COPD)	41	low	trained
GSM680080	Chronic Obstructive Pulmonary Disease (COPD)	39	low	trained
GSM680079	Chronic Obstructive Pulmonary Disease (COPD)	38	low	trained
GSM680078	Chronic Obstructive Pulmonary Disease (COPD)	37	low	trained
GSM680077	Chronic Obstructive Pulmonary Disease (COPD)	36	low	trained
GSM680076	Chronic Obstructive Pulmonary Disease (COPD)	42	low	sedentary
GSM680075	Chronic Obstructive Pulmonary Disease (COPD)	41	low	sedentary
GSM680074	Chronic Obstructive Pulmonary Disease (COPD)	39	low	sedentary
GSM680073	Chronic Obstructive Pulmonary Disease (COPD)	38	low	sedentary
GSM680072	Chronic Obstructive Pulmonary Disease (COPD)	37	low	sedentary
GSM68007	Chronic Obstructive Pulmonary Disease (COPD)	36	low	sedentary
GSM680070	Chronic Obstructive Pulmonary Disease (COPD)	34	normal	trained
GSM680069	Chronic Obstructive Pulmonary Disease (COPD)	30	normal	trained
GSM680068	Chronic Obstructive Pulmonary Disease (COPD)	27	normal	trained
GSM680067	Chronic Obstructive Pulmonary Disease (COPD)	25	normal	trained
GSM680066	Chronic Obstructive Pulmonary Disease (COPD)	24	normal	trained
GSM680065	Chronic Obstructive Pulmonary Disease (COPD)	22	normal	trained
GSM680064	Chronic Obstructive Pulmonary Disease (COPD)	20	normal	trained
GSM680063	Chronic Obstructive Pulmonary Disease (COPD)	18	normal	trained
GSM680062	Chronic Obstructive Pulmonary Disease (COPD)	17	normal	trained
GSM68006	Chronic Obstructive Pulmonary Disease (COPD)	34	normal	sedentary
GSM680060	Chronic Obstructive Pulmonary Disease (COPD)	30	normal	sedentary
GSM680059	Chronic Obstructive Pulmonary Disease (COPD)	27	normal	sedentary
GSM680058	Chronic Obstructive Pulmonary Disease (COPD)	25	normal	sedentary
GSM680057	Chronic Obstructive Pulmonary Disease (COPD)	24	normal	sedentary
GSM680056	Chronic Obstructive Pulmonary Disease (COPD)	22	normal	sedentary
GSM680055	Chronic Obstructive Pulmonary Disease (COPD)	20	normal	sedentary
GSM680054	Chronic Obstructive Pulmonary Disease (COPD)	18	normal	sedentary
GSM680053	Chronic Obstructive Pulmonary Disease (COPD)	17	normal	sedentary
GSM680052	healthy	9	normal	trained
GSM68005	healthy	8	normal	trained
GSM680050	healthy	7	normal	trained
GSM680049	healthy	5	normal	trained
GSM680048	healthy	4	normal	trained
GSM680047	healthy	2	normal	trained
GSM680046	healthy	15	normal	trained
GSM680045	healthy	13	normal	trained
GSM680044	healthy	12	normal	trained
GSM680043	healthy	11	normal	trained
GSM680042	healthy	10	normal	trained
GSM68004	healthy	1	normal	trained
GSM680040	healthy	9	normal	sedentary
GSM680039	healthy	8	normal	sedentary
GSM680038	healthy	7	normal	sedentary
GSM680037	healthy	5	normal	sedentary
GSM680036	healthy	4	normal	sedentary
GSM680035	healthy	2	normal	sedentary
GSM680034	healthy	15	normal	sedentary
GSM680033	healthy	13	normal	sedentary
GSM680032	healthy	12	normal	sedentary
GSM68003	healthy	11	normal	sedentary
GSM680030	healthy	10	normal	sedentary
GSM680029	healthy	1	normal	sedentary