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Home › Dataset Library › Dmrt1 (doublesex and mab-3 related transcription factor 1) conditional knockout expression analysis of P28 testes

Dataset: Dmrt1 (doublesex and mab-3 related transcription factor 1) conditional knockout expression analysis of P28 testes

Dmrt1 (doublesex and mab-3 related transcription factor 1) is a conserved transcriptional regulator of male differentiation required for...

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Dmrt1 (doublesex and mab-3 related transcription factor 1) is a conserved transcriptional regulator of male differentiation required for testicular development in vertebrates. This study examines the result of conditional removal of Dmrt1 from Sertoli cells in P28 testis tissue. Testes from P28 Dmrt1 flox/flox mice were compared to testes from P28 Dmrt1 flox/flox mice with the Sertoli cell-specific Sf1 (Nr5a1; MGI:1346833) or Dhh (MGI:94891) promoters driving Cre expression.

Species:
mouse

Samples:
8

Source:
E-GEOD-27261

PubMed:
21775990

Updated:
Dec.12, 2014

Registered:
Nov.11, 2014


Factors: (via ArrayExpress)
Sample GENOTYPE
GSM673862 Dmrt1 flox/flox with no Cre
GSM673862 Dmrt1 flox/flox with no Cre
GSM673864 Dmrt1 flox/flox with Dhh-cre
GSM673864 Dmrt1 flox/flox with Dhh-cre
GSM673866 Dmrt1 flox/flox with SF1-cre
GSM673866 Dmrt1 flox/flox with SF1-cre
GSM673866 Dmrt1 flox/flox with SF1-cre
GSM673866 Dmrt1 flox/flox with SF1-cre

Tags

  • cell
  • sertoli cell
  • testis

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