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Home › Dataset Library › Nonalcoholic fatty liver disease in AxB mice

Dataset: Nonalcoholic fatty liver disease in AxB mice

Spontaneous insulin resistance and NAFLD emerged in AxB F1 male mice with parent-of-origin effects such that AB6F1 (AJ dam x B6 sire)...

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Spontaneous insulin resistance and NAFLD emerged in AxB F1 male mice with parent-of-origin effects such that AB6F1 (AJ dam x B6 sire) were susceptible whereas B6AF1 (B6 dam x AJ sire) were resistant. We used microarrays to correlate gene expression with the NAFLD phenotype in 9-month-old male AB6F1 (affected) versus B6AF1 (unaffected) mice. Whole liver slices from two 9-month-old AB6F1 and B6AF1 males were collected for RNA extraction and hybridization on Affymetrix microarrays.

Species:
mouse

Samples:
4

Source:
E-GEOD-26225

Updated:
Dec.12, 2014

Registered:
Nov.11, 2014


Factors: (via ArrayExpress)
Sample STRAIN GENOTYPE/VARIATION
GSM64386 AJ dam x B6 sire AB6F1
GSM64386 AJ dam x B6 sire AB6F1
GSM643863 B6 dam x AJ sire B6AF1
GSM643863 B6 dam x AJ sire B6AF1

Tags

  • insulin
  • liver

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