Dataset: Nonalcoholic fatty liver disease in AxB mice
Spontaneous insulin resistance and NAFLD emerged in AxB F1 male mice with parent-of-origin effects such that AB6F1 (AJ dam x B6 sire)...
Spontaneous insulin resistance and NAFLD emerged in AxB F1 male mice with parent-of-origin effects such that AB6F1 (AJ dam x B6 sire) were susceptible whereas B6AF1 (B6 dam x AJ sire) were resistant. We used microarrays to correlate gene expression with the NAFLD phenotype in 9-month-old male AB6F1 (affected) versus B6AF1 (unaffected) mice. Whole liver slices from two 9-month-old AB6F1 and B6AF1 males were collected for RNA extraction and hybridization on Affymetrix microarrays.
- Species:
- mouse
- Samples:
- 4
- Source:
- E-GEOD-26225
- Updated:
- Dec.12, 2014
- Registered:
- Nov.11, 2014
Factors:
(via ArrayExpress)
Sample | STRAIN | GENOTYPE/VARIATION |
---|---|---|
GSM64386 | AJ dam x B6 sire | AB6F1 |
GSM64386 | AJ dam x B6 sire | AB6F1 |
GSM643863 | B6 dam x AJ sire | B6AF1 |
GSM643863 | B6 dam x AJ sire | B6AF1 |