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Home › Dataset Library › Expression data from lateral nasal gland of male B6, 129/Sv and Cyp2g1-null mice

Dataset: Expression data from lateral nasal gland of male B6, 129/Sv and Cyp2g1-null mice

In male Cyp2g1-null mice, the lateral nasal gland, one of the largest anterior glands in the nasal cavity, was found to be protected from...

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In male Cyp2g1-null mice, the lateral nasal gland, one of the largest anterior glands in the nasal cavity, was found to be protected from acetaminophen toxicity. The goal of this study was to identify the genes that are involved in the mechanisms, especially those genes functional in drug metabolism, clearance and post-activation events. Lateral nasal gland from 2-3-month-old male mice were dissected from each strain of mouse (B6, 129/Sv and Cyp2g1-null). Both B6 and 129/Sv are used as control mice because the Cyp2g1-null mice are on the mixed genetic background. Glands from 10 mice of each strain were pooled for RNA preparaion for one chip. There are totally 9 chips including 2 for 129/Sv, four for B6 and 3 for Cyp2g1-null mice, respectively.

Species:
mouse

Samples:
9

Source:
E-GEOD-26056

Updated:
Dec.12, 2014

Registered:
Nov.24, 2014


Factors: (via ArrayExpress)
Sample STRAIN GENOTYPE
GSM639846 129/Sv wild type
GSM639846 129/Sv wild type
GSM639848 C57BL/6 wild type
GSM639848 C57BL/6 wild type
GSM639848 C57BL/6 wild type
GSM639848 C57BL/6 wild type
GSM639852 129/Sv x C57BL/6 mixed Cyp2g1-null
GSM639852 129/Sv x C57BL/6 mixed Cyp2g1-null
GSM639852 129/Sv x C57BL/6 mixed Cyp2g1-null

Tags

  • anterior
  • gland
  • lateral
  • nasal cavity

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