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Home › Dataset Library › Mesenchymal Nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation

Dataset: Mesenchymal Nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation

We generated Nfibf/f mice and then cross with Dermo1-Cre mice to obtain Nfibf/f, Dermo1-Cre mice. In these Nfibf/f, Dermo1-Cre mice,...

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We generated Nfibf/f mice and then cross with Dermo1-Cre mice to obtain Nfibf/f, Dermo1-Cre mice. In these Nfibf/f, Dermo1-Cre mice, there are defects in sacculation and epithelial cell differentiation. We performed micoarray analysis to find the genes which are possibley regulated by NFI-B and related to lung maturation during lung development. We used microarrays to performing transcriptional profiling of Nfibf/f, Dermo1-Cre and Nfibf/f lungs at E18.5

Species:
mouse

Samples:
6

Source:
E-GEOD-24465

Updated:
Dec.12, 2014

Registered:
Nov.11, 2014


Factors: (via ArrayExpress)
Sample GENOTYPE
GSM602679 Nfibf/f
GSM602679 Nfibf/f
GSM602679 Nfibf/f
GSM602682 Nfibf/f, Dermo1-Cre
GSM602682 Nfibf/f, Dermo1-Cre
GSM602682 Nfibf/f, Dermo1-Cre

Tags

  • cell
  • epithelial cell
  • lung

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