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Home › Dataset Library › PCPTC screening

Dataset: PCPTC screening

Primary cultures of patient tumor cells (PCPTC) were used in a cell-based cytotoxicity screen. Microarray-based mRNA profiling was used...

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Primary cultures of patient tumor cells (PCPTC) were used in a cell-based cytotoxicity screen. Microarray-based mRNA profiling was used to identify the mechanism-of-action for the small molecule VLX 50. MCF7 cells were treated with the PCPTC screening hit VLX 50 or DMSO control for 6h prior to RNA isolation. One sample per treatment. Data were analyzed using both MAS5.0 and RMA.

Species:
human

Samples:
4

Source:
E-GEOD-24027

PubMed:
21531212

Updated:
Dec.12, 2014

Registered:
Sep.15, 2014


Factors: (via ArrayExpress)
Sample SAMPLE TYPE CONCENTRATION TREATMENT
GSM59145 treatment 0.00001 M VLX 50
GSM591452 control 0.1% DMSO
GSM59145 treatment 0.00001 M VLX 50
GSM591452 control 0.1% DMSO

Tags

  • cell

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