Dataset: Expression data from breast cancer FNA biopsies from patients (US samples)
This is Phase II Trial of 4courses of 5-fluorouracil, doxorubicin and cyclophosphamide follwed by 4 additional courses of weekly...
This is Phase II Trial of 4courses of 5-fluorouracil, doxorubicin and cyclophosphamide follwed by 4 additional courses of weekly docetaxel and capecitabine administered as Preoperative Therapy for Patients with Locally Advanced Breast Cancer, Stages II and III by US oncology (PROTOCOL 02-103) We performed gene set analysis (GSA) using functionally annotated gene sets corresponding to almost all known biological processes in ER-positive/HER2negative and ER-negative/HER2-negative breast cancer, respectively. Pre-treatment FNA from primary tumors were obtained and RNA extracted and hybridized to afymetrix microarrays according to manufacturer protocol.
- Species:
- human
- Samples:
- 61
- Source:
- E-GEOD-23988
- PubMed:
- 21191116
- Updated:
- Dec.12, 2014
- Registered:
- Jun.19, 2014
| Sample | PCR.V.RD | ER POSITIVE VS NEGATIVE | GRADE | AGE | PRECHEMO NODAL STATUS | PRECHEMO TUMOR SIZE | PRECHEMO T STAGE |
|---|---|---|---|---|---|---|---|
| GSM590900 | RD | ERpos | 3 | 44.225 | 1 | 4 | 2 |
| GSM590899 | RD | ERpos | 2 | 58.130 | 2 | 6 | 3 |
| GSM590898 | RD | ERneg | 3 | 61.073 | 0 | 3.4 | 2 |
| GSM590897 | RD | ERpos | 2 | 57.654 | 1 | 3 | 2 |
| GSM590896 | pCR | ERneg | NA | 52.808 | 0 | 4 | 2 |
| GSM590895 | RD | ERpos | 2 | 46.004 | 1 | 3.5 | 2 |
| GSM590894 | pCR | ERneg | 3 | 45.963 | 3 | 6 | 3 |
| GSM590893 | RD | ERpos | 3 | 45.232 | 0 | 6 | 3 |
| GSM590892 | RD | ERpos | 3 | 54.549 | 0 | 5 | 2 |
| GSM59089 | RD | ERpos | 2 | 42.565 | 1 | 5.5 | 3 |
| GSM590890 | pCR | ERneg | 3 | 48.433 | 0 | 8 | 3 |
| GSM590889 | pCR | ERneg | 3 | 46.782 | 1 | 4 | 2 |
| GSM590888 | RD | ERpos | 2 | 34.075 | 0 | 6 | 3 |
| GSM590887 | RD | ERpos | 2 | 47.899 | 1 | 10 | 3 |
| GSM590886 | RD | ERneg | 3 | 32.578 | 1 | 2 | 1 |
| GSM590885 | pCR | ERneg | NA | 49.607 | 0 | 6.5 | 3 |
| GSM590884 | RD | ERneg | 2 | 38.593 | 0 | 13 | 3 |
| GSM590883 | RD | ERpos | 2 | 52.485 | 0 | 7 | 3 |
| GSM590882 | pCR | ERpos | 3 | 40.337 | 2 | 2.3 | 2 |
| GSM59088 | pCR | ERpos | 3 | 47.392 | 0 | 7 | 3 |
| GSM590880 | RD | ERneg | 3 | 55.658 | 1 | 6 | 3 |
| GSM590879 | RD | ERneg | 3 | 66.710 | 1 | 5.5 | 3 |
| GSM590878 | pCR | ERpos | 2 | 50.056 | 1 | 4 | 2 |
| GSM590877 | RD | ERneg | 3 | 33.539 | 2 | 11.8 | 3 |
| GSM590876 | RD | ERpos | 3 | 44.402 | 1 | 6 | 3 |
| GSM590875 | pCR | ERpos | 3 | 52.745 | 1 | 10 | 3 |
| GSM590874 | pCR | ERneg | 3 | 40.687 | 3 | 3.5 | 2 |
| GSM590873 | RD | ERneg | 3 | 62.341 | 1 | 2.5 | 2 |
| GSM590872 | RD | ERpos | 2 | 59.472 | 1 | 10 | 3 |
| GSM59087 | RD | ERneg | 3 | 43.893 | 2 | 5.5 | 3 |
| GSM590870 | pCR | ERneg | 2 | 49.246 | 0 | 7.5 | 3 |
| GSM590869 | pCR | ERneg | 3 | 50.300 | 1 | 3.5 | 2 |
| GSM590868 | RD | ERpos | NA | 26.086 | 1 | 14 | 3 |
| GSM590867 | RD | ERneg | 3 | 66.820 | 1 | 11.5 | 3 |
| GSM590866 | RD | ERpos | 3 | 45.109 | 1 | 11 | 3 |
| GSM590865 | RD | ERpos | 2 | 55.934 | 1 | 8 | 3 |
| GSM590864 | RD | ERneg | 2 | 60.860 | 1 | 4 | 2 |
| GSM590863 | RD | ERpos | 3 | 41.273 | 1 | 5.3 | 3 |
| GSM590862 | RD | ERneg | 3 | 65.314 | 2 | 17.5 | 3 |
| GSM59086 | RD | ERpos | 3 | 60.099 | 0 | 6 | 3 |
| GSM590860 | pCR | ERneg | 3 | 51.132 | 1 | 6 | 3 |
| GSM590859 | RD | ERpos | 1 | 45.363 | 0 | 4 | 2 |
| GSM590858 | RD | ERneg | 3 | 59.231 | 0 | 15 | 3 |
| GSM590857 | RD | ERpos | 2 | 51.461 | 0 | 6.5 | 3 |
| GSM590856 | RD | ERpos | 3 | 46.943 | 1 | 6 | 3 |
| GSM590855 | pCR | ERneg | 3 | 50.064 | 1 | 7.5 | 3 |
| GSM590854 | RD | ERpos | 3 | 53.988 | 0 | 6 | 3 |
| GSM590853 | RD | ERneg | 2 | 65.054 | 1 | 11 | 3 |
| GSM590852 | RD | ERneg | 3 | 49.010 | 0 | 6 | 3 |
| GSM59085 | RD | ERneg | 3 | 40.337 | 1 | 5 | 2 |
| GSM590850 | pCR | ERneg | 3 | 43.028 | 1 | 8 | 3 |
| GSM590849 | RD | ERpos | 3 | 57.536 | 1 | 5 | 2 |
| GSM590848 | pCR | ERneg | 3 | 34.059 | 0 | 7 | 3 |
| GSM590847 | RD | ERpos | 2 | 47.118 | 1 | 7 | 3 |
| GSM590846 | pCR | ERpos | 3 | 50.771 | 1 | 10 | 3 |
| GSM590845 | pCR | ERpos | 3 | 43.775 | 3 | 8 | 3 |
| GSM590844 | pCR | ERpos | 2 | 47.099 | 0 | 3.5 | 2 |
| GSM590843 | RD | ERpos | 2 | 36.739 | 1 | 4 | 2 |
| GSM590842 | pCR | ERneg | 3 | 41.914 | 1 | 3 | 2 |
| GSM59084 | RD | ERpos | 2 | 32.197 | 0 | 4.5 | 2 |
| GSM590840 | RD | ERneg | NA | 46.209 | 0 | 6 | 3 |