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Home › Dataset Library › Comparative gene expression analysis of mesenchymal stem cells (MSC) derived from non-small cell lung cancer (NSCLC) and corresponding...

Dataset: Comparative gene expression analysis of mesenchymal stem cells (MSC) derived from non-small cell lung cancer (NSCLC) and corresponding normal lung tissue (NLT)

The stromal microenvironment plays a vital role in cancer initiation and progression. We performed a comparative expression profiling of...

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The stromal microenvironment plays a vital role in cancer initiation and progression. We performed a comparative expression profiling of pulmonary MSC derived from NSCLC and corresponding normal lung tissue of 5 newly diagnosed patients. The analysis indicated variable expression of genes involved in DNA repair, apoptosis, proliferation or angiogenesis between NSCLC-MSC and NLT-MSC. MSC were derived from NSCLC and corresponding normal lung tissue of 5 patients. Paired SAM test was performed to screen for differentially expressed genes between NSCLC-MSC and NLT-MSC.

Species:
human

Samples:
10

Source:
E-GEOD-23066

PubMed:
23294501

Updated:
Dec.12, 2014

Registered:
Jul.12, 2014


Factors: (via ArrayExpress)
Sample PATIENT CELL TYPE
GSM568888 2299 NSCLC-associated fibroblast
GSM568887 2299 normal bronchial fibroblast
GSM568886 2183 NSCLC-associated fibroblast
GSM568885 2183 normal bronchial fibroblast
GSM568884 2106 NSCLC-associated fibroblast
GSM568883 2106 normal bronchial fibroblast
GSM568882 1061 NSCLC-associated fibroblast
GSM56888 1061 normal bronchial fibroblast
GSM568880 13 NSCLC-associated fibroblast
GSM568879 13 normal bronchial fibroblast

Tags

  • cancer
  • lung
  • nsclc

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