Dataset: Expression profiles from a variety of resting and activated human immune cells
Immune cell-specific expression is one indication of the importance of a gene's role in the immune response. In order to identify such...
Immune cell-specific expression is one indication of the importance of a gene's role in the immune response. In order to identify such patterns, we set out to broadly profile gene expression in a variety of immune cells. We isolated twelve different types of human leukocytes from peripheral blood and bone marrow, treated them to induce activation and/or differentiation, and profiled their gene expression before and after treatment. The twelve cell types are: B cells, CD14+ cells, CD4+ CD45RO+ CD45RA- T cells, CD4+ T cells, CD8+ T cells, IgG/IgA memory B cells, IgM memory B cells, Monocytes, NK cells, Neutrophils, Plasma cells from bone marrow, and Plasma cells from PBMC.
- Species:
- human
- Samples:
- 114
- Source:
- E-GEOD-22886
- PubMed:
- 15789058
- Updated:
- Jan.17, 2015
- Registered:
- Jan.17, 2015
Factors:
(via ArrayExpress)
| Sample | TREATMENT AGENT | TISSUE | CELL TYPE | TIME POST-TREATMENT |
|---|---|---|---|---|
| GSM565269 1 | nan | peripheral blood | CD8+ T cells | nan |
| GSM565270 1 | nan | peripheral blood | CD8+ T cells | nan |
| GSM565271 1 | nan | peripheral blood | CD8+ T cells | nan |
| GSM565272 1 | nan | peripheral blood | CD8+ T cells | nan |
| GSM565273 1 | nan | peripheral blood | CD4+ T cells | control |
| GSM565274 1 | nan | peripheral blood | CD4+ T cells | control |
| GSM565275 1 | nan | peripheral blood | CD4+ T cells | control |
| GSM565276 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 12 hrs |
| GSM565277 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 12 hrs |
| GSM565278 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 48 hrs |
| GSM565279 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 48 hrs |
| GSM565280 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 48 hrs |
| GSM565281 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 12 hrs |
| GSM565282 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 12 hrs |
| GSM565283 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 12 hrs |
| GSM565284 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 48 hrs |
| GSM565285 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 48 hrs |
| GSM565286 1 | aCD3/aCD28 | peripheral blood | CD4+ T cells | 48 hrs |
| GSM565287 1 | nan | peripheral blood | CD4+ CD45RO+ CD45RA- T cells | nan |
| GSM565288 1 | nan | peripheral blood | CD4+ CD45RO+ CD45RA- T cells | nan |
| GSM565289 1 | nan | peripheral blood | CD4+ CD45RO+ CD45RA- T cells | nan |
| GSM565290 1 | aCD3/aCD28 | peripheral blood | CD4+ CD45RO+ CD45RA- T cells | nan |
| GSM565291 1 | aCD3/aCD28 | peripheral blood | CD4+ CD45RO+ CD45RA- T cells | nan |
| GSM565292 1 | aCD3/aCD28 | peripheral blood | CD4+ CD45RO+ CD45RA- T cells | nan |
| GSM565293 1 | nan | peripheral blood | NK cells | nan |
| GSM565294 1 | nan | peripheral blood | NK cells | nan |
| GSM565295 1 | nan | peripheral blood | NK cells | nan |
| GSM565296 1 | nan | peripheral blood | NK cells | nan |
| GSM565297 1 | IL2 | peripheral blood | NK cells | nan |
| GSM565298 1 | IL2 | peripheral blood | NK cells | nan |
| GSM565299 1 | IL2 | peripheral blood | NK cells | nan |
| GSM565300 1 | IL2 | peripheral blood | NK cells | nan |
| GSM565301 1 | IL2 | peripheral blood | NK cells | nan |
| GSM565302 1 | IL15 | peripheral blood | NK cells | nan |
| GSM565303 1 | IL15 | peripheral blood | NK cells | nan |
| GSM565304 1 | IL15 | peripheral blood | NK cells | nan |
| GSM565305 1 | IL15 | peripheral blood | NK cells | nan |
| GSM565306 1 | IL15 | peripheral blood | NK cells | nan |
| GSM565307 1 | IL15 | peripheral blood | NK cells | nan |
| GSM565308 1 | nan | peripheral blood | B cells | nan |
| GSM565309 1 | nan | peripheral blood | B cells | nan |
| GSM565310 1 | nan | peripheral blood | B cells | nan |
| GSM565311 1 | nan | peripheral blood | B cells | nan |
| GSM565312 1 | nan | peripheral blood | B cells | nan |
| GSM565313 1 | nan | peripheral blood | B cells | nan |
| GSM565314 1 | nan | peripheral blood | B cells | nan |
| GSM565315 1 | nan | peripheral blood | IgG/IgA memory B cells | nan |
| GSM565316 1 | nan | peripheral blood | IgG/IgA memory B cells | nan |
| GSM565317 1 | nan | peripheral blood | IgG/IgA memory B cells | nan |
| GSM565318 1 | nan | peripheral blood | IgG/IgA memory B cells | nan |
| GSM565319 1 | nan | peripheral blood | IgM memory B cells | nan |
| GSM565320 1 | nan | peripheral blood | IgM memory B cells | nan |
| GSM565321 1 | nan | peripheral blood | IgM memory B cells | nan |
| GSM565322 1 | nan | peripheral blood | IgM memory B cells | nan |
| GSM565323 1 | nan | peripheral blood | Plasma cells | nan |
| GSM565324 1 | nan | peripheral blood | Plasma cells | nan |
| GSM565325 1 | nan | peripheral blood | Plasma cells | nan |
| GSM565326 1 | nan | bone marrow | Plasma cells | nan |
| GSM565327 1 | nan | bone marrow | Plasma cells | nan |
| GSM565328 1 | nan | bone marrow | Plasma cells | nan |
| GSM565329 1 | nan | bone marrow | Plasma cells | nan |
| GSM565330 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565331 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565332 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565333 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565334 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565335 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565336 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565337 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565338 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565339 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565340 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565341 1 | nan | peripheral blood | Monocytes | 0 day |
| GSM565342 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565343 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565344 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565345 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565346 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565347 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565348 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565349 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565350 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565351 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565352 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565353 1 | macrophage differentiation medium | peripheral blood | Monocytes | 1 day |
| GSM565354 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565355 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565356 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565357 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565358 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565359 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565360 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565361 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565362 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565363 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565364 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565365 1 | macrophage differentiation medium | peripheral blood | Monocytes | 7 day |
| GSM565366 1 | nan | peripheral blood | CD14+ cells | control |
| GSM565367 1 | nan | peripheral blood | CD14+ cells | control |
| GSM565368 1 | nan | peripheral blood | CD14+ cells | control |
| GSM565369 1 | nan | peripheral blood | CD14+ cells | control |
| GSM565370 1 | nan | peripheral blood | CD14+ cells | control |
| GSM565371 1 | nan | peripheral blood | CD14+ cells | control |
| GSM565372 1 | LPS | peripheral blood | CD14+ cells | 24 hrs |
| GSM565373 1 | LPS | peripheral blood | CD14+ cells | 24 hrs |
| GSM565374 1 | LPS | peripheral blood | CD14+ cells | 24 hrs |
| GSM565375 1 | LPS | peripheral blood | CD14+ cells | 24 hrs |
| GSM565376 1 | LPS | peripheral blood | CD14+ cells | 24 hrs |
| GSM565377 1 | LPS | peripheral blood | CD14+ cells | 24 hrs |
| GSM565378 1 | nan | peripheral blood | Neutrophils | nan |
| GSM565379 1 | nan | peripheral blood | Neutrophils | nan |
| GSM565380 1 | nan | peripheral blood | Neutrophils | nan |
| GSM565381 1 | nan | peripheral blood | Neutrophils | nan |
| GSM565382 1 | nan | peripheral blood | Neutrophils | nan |