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Home › Dataset Library › Effect of TIF1γ gene deletion on hematopoietic stem cells

Dataset: Effect of TIF1γ gene deletion on hematopoietic stem cells

Analysis of KLS cells purified from bone marrow of mice conditionally inactivated for TIF1γ gene. TIF1γ deletion results in multiple...

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Analysis of KLS cells purified from bone marrow of mice conditionally inactivated for TIF1γ gene. TIF1γ deletion results in multiple defects in adult hematopoiesis. Results provide insight into the role of TIF1γ in hematopoietic stem cells functions. We used microarrays to characterize the molecular mechanisms underlying the biological properties of KLS cells lacking TIF1γ KLS (lin-,c-kit+, Sca+) cells were purified by cell sorting

Species:
mouse

Samples:
2

Source:
E-GEOD-22280

PubMed:
21474105

Updated:
Dec.12, 2014

Registered:
Nov.11, 2014


Factors: (via ArrayExpress)
Sample GENOTYPE
GSM554392 wild type
GSM554393 TIF1γ Δ/Δ

Tags

  • bone
  • bone marrow
  • cell

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