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Home › Dataset Library › Female human iPS cells retain an inactive X-chromosome

Dataset: Female human iPS cells retain an inactive X-chromosome

Comparison of human iPSC lines, ESC and fibroblasts to determine their expression patterns. All early passage female lines profiled...

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Comparison of human iPSC lines, ESC and fibroblasts to determine their expression patterns. All early passage female lines profiled expressed XIST RNA which is an indicator of an inactive X chromosome. Genes on the X-chromosome were also analyzed for overall levels of gene expression compared to human fibroblasts. hiPSC lines were generated and extracted for RNA with TriZOL and hybridization on Affymetrix arrays.

Species:
human

Samples:
13

Source:
E-GEOD-22246

PubMed:
20727844

Updated:
Dec.12, 2014

Registered:
Sep.15, 2014


Factors: (via ArrayExpress)
Sample CELL LINE CELL TYPE
GSM5537 HSF1 Human embryonic stem cell line
GSM553712 H9 Human embryonic stem cell line
GSM553713 H1 Human embryonic stem cell line
GSM553714 hiPSC line 1 hiPSC cell line
GSM553715 hiPSC line 2 hiPSC cell line
GSM553716 hiPSC line 18 hiPSC cell line
GSM553717 hiPSC 3975 hiPSC cell line
GSM553718 hiPSC E hiPSC cell line
GSM553719 hiPSC G hiPSC cell line
GSM553720 hiPSC pMIP2 hiPSC cell line
GSM55372 hiPSC pMIP3 Fibroblast cell line
GSM553722 IMR90 Fibroblast cell line
GSM553723 NHDF 17914 Fibroblast cell line

Tags

  • chromosome
  • x chromosome

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