Dataset: Expression Data from Uveal Melanoma primary tumors.

A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes...

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A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes associated with metastasis in this pathology, we studied 63 molecular profiles derived from gene expression microarrays performed from enuceated primary tumors. Metastasis free survival analysis was performed to obtain clinical and genomic variables associated to metastasis occurrence. We also compared within the 57 tumors with at least 36 months follow-up, 28 uveal melanoma from patients who developed liver metastases (meta1 group) with 29 tumors arising from patients without metastases (or later metastases, i.e. after 36 months) (meta0 group). The transcriptome of 63 uveal melanoma from enucleation of untreated patients were analyzed using Affymetrix U133plus2 Arrays.

Species:: human
Samples:: 63
Source:: E-GEOD-22138
PubMed:: 21135111
Updated:: Dec.12, 2014
Registered:: Sep.15, 2014

Factors: (via ArrayExpress)

Sample	CHROMOSOME 3 STATUS	TUMOR DIAMETER (MM)	EYE	GENDER	TUMOR CELL TYPE	METASTASIS	RETINAL DETACHMENT	AGE	EXTRASCLERAL EXTENSION	TUMOR LOCATION	TUMOR THICKNESS (MM)	MONTHS TO ENDPOINT
GSM550623	nan	nan	right	female	mixed	no	no	76.54	nan	nan	12.2	73.0
GSM550624	nan	10	left	male	epithelioid	yes	nan	67.57	nan	on equator	11.3	32.13
GSM550625	nan	20	right	male	nan	yes	yes	61.82	nan	on equator	10.9	0.39
GSM550626	disomy	15	right	male	mixed	yes	yes	46.4	yes	posterior to equator	14	64.0
GSM550627	monosomy	20	right	male	nan	no	no	84.99	nan	anterior to equator		67.81
GSM550628	disomy	nan	left	female	mixed	no	yes	50.64	no	on equator	8.3	86.08
GSM550629	disomy	11	right	male	nan	no	yes	38.67	no	on equator	10	85.09
GSM550630	monosomy	20.9	right	male	epithelioid	yes	yes	59.1	no	on equator	10.5	6.14
GSM55063	disomy	19.4	left	male	mixed	no	yes	52.33	no	on equator	13.7	55.79
GSM550632	disomy	15	right	male	mixed	no	no	32.94	no	on equator	10.1	55.23
GSM550633	monosomy	13	right	male	mixed	yes	yes	70.09	no	on equator	13.8	7.92
GSM550634	nan	15	left	male	mixed	yes	yes	60.8	nan	posterior to equator	7.5	16.76
GSM550635	monosomy	13	left	female	mixed	yes	yes	54.81	yes	on equator	12.7	0.92
GSM550636	nan	15	left	male	nan	yes	yes	75.66	no	on equator	12.4	6.54
GSM550637	partial monosomy		right	male	mixed	no	yes	45.97	no	on equator	10.4	89.82
GSM550638	monosomy	12	left	female	epithelioid	yes	no	51.61	no	on equator	10.5	21.78
GSM550639	nan		right	female	mixed	no	no	66.2	nan	nan	8.9	120.64
GSM550640	disomy	23	left	female	mixed	no	no	51.95	no	on equator	15	95.47
GSM55064	monosomy	nan	left	male	nan	no	no	59.41	no	posterior to equator	12	25.13
GSM550642	monosomy	10	left	male	nan	no	yes	68.51	no	nan	8.9	60.06
GSM550643	monosomy	16	right	male	nan	no	yes	65.62	no	on equator	13	14.16
GSM550644	disomy	17	left	female	mixed	no	yes	47.62	no	on equator	9.7	67.98
GSM550645	nan	21	right	male	mixed	yes	yes	69.09	nan	all over the eye	14	7.06
GSM550646	monosomy	12	right	female	epithelioid	yes	yes	75.75	nan	posterior and on equator	10	8.67
GSM550647	monosomy	18	left	female	nan	yes	yes	67.46	no	on equator	11.7	49.02
GSM550648	monosomy	15	left	female	nan	yes	yes	40.41	no	on equator	11.4	28.88
GSM550649	partial monosomy	22	left	male	epithelioid	yes	yes	72.29	no	nan	14	20.99
GSM550650	monosomy	13	left	male	mixed	no	no	62.62	no	on equator	13	100.4
GSM55065	partial monosomy	15	right	female	mixed	no	no	51.91	no	posterior to equator	11	85.82
GSM550652	monosomy	10	right	male	epithelioid	yes	no	63.03	no	anterior to equator	11	24.54
GSM550653	partial monosomy	nan	right	male	mixed	yes	yes	65.2	no	on equator	12.8	35.78
GSM550654	disomy	18	right	male	nan	no	yes	40.31	no	on equator	11	55.75
GSM550655	disomy	17	left	female	mixed	no	no	28.56	nan	on equator	13	90.02
GSM550656	disomy	16	left	male	nan	no	yes	57.69	no	posterior to equator	10.5	93.73
GSM550657	monosomy	19	left	female	epithelioid	yes	yes	55.68	no	on equator	11.7	27.3
GSM550658	disomy	20	left	male	mixed	no	no	72.82	no	on equator	14	70.14
GSM550659	partial monosomy	17	right	female	nan	yes	yes	47.43	nan	posterior and on equator	13.5	52.57
GSM550660	monosomy	nan	left	male	epithelioid	no	no	78.98	no	nan	11.1	39.69
GSM55066	monosomy	16	right	female	epithelioid	yes	no	77.95	no	on equator	11.7	18.96
GSM550662	monosomy	nan	left	male	epithelioid	yes	no	62.88	no	on equator	11.5	12.88
GSM550663	monosomy	10	left	female	epithelioid	yes	yes	54.41	no	on equator	9.3	0.13
GSM550664	monosomy	11	right	female	epithelioid	yes	no	77.68	no	anterior to equator	11.8	24.44
GSM550665	disomy	19	left	female	nan	no	no	56.17	no	on equator	12	62.69
GSM550666	monosomy	20	left	male	epithelioid	no	no	72.79	no	on equator	12.4	67.75
GSM550667	monosomy	16	right	female	nan	yes	nan	53.07	yes	posterior to equator		68.37
GSM550668	monosomy	12	left	male	nan	yes	yes	48.46	no	on equator	10.5	14.95
GSM550669	nan	11	right	female	epithelioid	yes	yes	68.83	no	posterior and on equator	11.5	58.74
GSM550670	monosomy	nan	left	male	mixed	yes	yes	62.12	no	posterior to equator	17	18.89
GSM55067	monosomy	nan	right	male	epithelioid	yes	yes	56.33	no	posterior to equator	9.9	7.33
GSM550672	disomy	17	right	male	mixed	yes	no	68.36	yes	on equator	11.5	35.55
GSM550673	monosomy	nan	right	male	epithelioid	yes	nan	69.05	no	posterior to equator	13	8.34
GSM550674	disomy	10	right	male	epithelioid	no	yes	50.17	no	on equator		31.18
GSM550675	disomy	15	right	female	epithelioid	no	yes	56.25	no	on equator	11	67.38
GSM550676	monosomy	17	right	female	nan	no	no	82.79	no	on equator	13.2	31.54
GSM550677	disomy	15	right	male	mixed	yes	yes	70.26	no	on equator	13	6.18
GSM550678	monosomy	18	left	male	nan	no	no	80.66	no	on equator	11	9.3
GSM550679	monosomy	19.6	left	male	epithelioid	yes	yes	50.17	no	on equator	13.6	17.61
GSM550680	disomy	15	left	male	epithelioid	no	nan	66.26	no	on equator	10.5	31.74
GSM55068	monosomy	12	left	female	epithelioid	no	yes	56.1	no	on equator	13.7	50.46
GSM550682	monosomy	10	left	male	mixed	yes	yes	64.55	no	on equator	15	14.85
GSM550683	disomy	16	left	male	nan	yes	yes	60.35	yes	on equator	12.5	36.9
GSM550684	monosomy	20	left	female	mixed	yes	no	65.72	no	on equator	14	44.39
GSM550685	monosomy	nan	right	male	nan	yes	nan	73.13	no	on equator	13	7.59