Dataset: Expression Data from Uveal Melanoma primary tumors.

A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes...

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A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes associated with metastasis in this pathology, we studied 63 molecular profiles derived from gene expression microarrays performed from enuceated primary tumors. Metastasis free survival analysis was performed to obtain clinical and genomic variables associated to metastasis occurrence. We also compared within the 57 tumors with at least 36 months follow-up, 28 uveal melanoma from patients who developed liver metastases (meta1 group) with 29 tumors arising from patients without metastases (or later metastases, i.e. after 36 months) (meta0 group). The transcriptome of 63 uveal melanoma from enucleation of untreated patients were analyzed using Affymetrix U133plus2 Arrays.

Species:: human
Samples:: 63
Source:: E-GEOD-22138
PubMed:: 21135111
Updated:: Dec.12, 2014
Registered:: Sep.15, 2014

Factors: (via ArrayExpress)

Sample	CHROMOSOME 3 STATUS	TUMOR DIAMETER (MM)	AGE	TUMOR LOCATION	GENDER	TUMOR CELL TYPE	METASTASIS	RETINAL DETACHMENT	EXTRASCLERAL EXTENSION	EYE	TUMOR THICKNESS (MM)	MONTHS TO ENDPOINT
GSM550623	nan	nan	76.54	nan	female	mixed	no	no	nan	right	12.2	73.0
GSM550624	nan	10	67.57	on equator	male	epithelioid	yes	nan	nan	left	11.3	32.13
GSM550625	nan	20	61.82	on equator	male	nan	yes	yes	nan	right	10.9	0.39
GSM550626	disomy	15	46.4	posterior to equator	male	mixed	yes	yes	yes	right	14	64.0
GSM550627	monosomy	20	84.99	anterior to equator	male	nan	no	no	nan	right		67.81
GSM550628	disomy	nan	50.64	on equator	female	mixed	no	yes	no	left	8.3	86.08
GSM550629	disomy	11	38.67	on equator	male	nan	no	yes	no	right	10	85.09
GSM550630	monosomy	20.9	59.1	on equator	male	epithelioid	yes	yes	no	right	10.5	6.14
GSM55063	disomy	19.4	52.33	on equator	male	mixed	no	yes	no	left	13.7	55.79
GSM550632	disomy	15	32.94	on equator	male	mixed	no	no	no	right	10.1	55.23
GSM550633	monosomy	13	70.09	on equator	male	mixed	yes	yes	no	right	13.8	7.92
GSM550634	nan	15	60.8	posterior to equator	male	mixed	yes	yes	nan	left	7.5	16.76
GSM550635	monosomy	13	54.81	on equator	female	mixed	yes	yes	yes	left	12.7	0.92
GSM550636	nan	15	75.66	on equator	male	nan	yes	yes	no	left	12.4	6.54
GSM550637	partial monosomy		45.97	on equator	male	mixed	no	yes	no	right	10.4	89.82
GSM550638	monosomy	12	51.61	on equator	female	epithelioid	yes	no	no	left	10.5	21.78
GSM550639	nan		66.2	nan	female	mixed	no	no	nan	right	8.9	120.64
GSM550640	disomy	23	51.95	on equator	female	mixed	no	no	no	left	15	95.47
GSM55064	monosomy	nan	59.41	posterior to equator	male	nan	no	no	no	left	12	25.13
GSM550642	monosomy	10	68.51	nan	male	nan	no	yes	no	left	8.9	60.06
GSM550643	monosomy	16	65.62	on equator	male	nan	no	yes	no	right	13	14.16
GSM550644	disomy	17	47.62	on equator	female	mixed	no	yes	no	left	9.7	67.98
GSM550645	nan	21	69.09	all over the eye	male	mixed	yes	yes	nan	right	14	7.06
GSM550646	monosomy	12	75.75	posterior and on equator	female	epithelioid	yes	yes	nan	right	10	8.67
GSM550647	monosomy	18	67.46	on equator	female	nan	yes	yes	no	left	11.7	49.02
GSM550648	monosomy	15	40.41	on equator	female	nan	yes	yes	no	left	11.4	28.88
GSM550649	partial monosomy	22	72.29	nan	male	epithelioid	yes	yes	no	left	14	20.99
GSM550650	monosomy	13	62.62	on equator	male	mixed	no	no	no	left	13	100.4
GSM55065	partial monosomy	15	51.91	posterior to equator	female	mixed	no	no	no	right	11	85.82
GSM550652	monosomy	10	63.03	anterior to equator	male	epithelioid	yes	no	no	right	11	24.54
GSM550653	partial monosomy	nan	65.2	on equator	male	mixed	yes	yes	no	right	12.8	35.78
GSM550654	disomy	18	40.31	on equator	male	nan	no	yes	no	right	11	55.75
GSM550655	disomy	17	28.56	on equator	female	mixed	no	no	nan	left	13	90.02
GSM550656	disomy	16	57.69	posterior to equator	male	nan	no	yes	no	left	10.5	93.73
GSM550657	monosomy	19	55.68	on equator	female	epithelioid	yes	yes	no	left	11.7	27.3
GSM550658	disomy	20	72.82	on equator	male	mixed	no	no	no	left	14	70.14
GSM550659	partial monosomy	17	47.43	posterior and on equator	female	nan	yes	yes	nan	right	13.5	52.57
GSM550660	monosomy	nan	78.98	nan	male	epithelioid	no	no	no	left	11.1	39.69
GSM55066	monosomy	16	77.95	on equator	female	epithelioid	yes	no	no	right	11.7	18.96
GSM550662	monosomy	nan	62.88	on equator	male	epithelioid	yes	no	no	left	11.5	12.88
GSM550663	monosomy	10	54.41	on equator	female	epithelioid	yes	yes	no	left	9.3	0.13
GSM550664	monosomy	11	77.68	anterior to equator	female	epithelioid	yes	no	no	right	11.8	24.44
GSM550665	disomy	19	56.17	on equator	female	nan	no	no	no	left	12	62.69
GSM550666	monosomy	20	72.79	on equator	male	epithelioid	no	no	no	left	12.4	67.75
GSM550667	monosomy	16	53.07	posterior to equator	female	nan	yes	nan	yes	right		68.37
GSM550668	monosomy	12	48.46	on equator	male	nan	yes	yes	no	left	10.5	14.95
GSM550669	nan	11	68.83	posterior and on equator	female	epithelioid	yes	yes	no	right	11.5	58.74
GSM550670	monosomy	nan	62.12	posterior to equator	male	mixed	yes	yes	no	left	17	18.89
GSM55067	monosomy	nan	56.33	posterior to equator	male	epithelioid	yes	yes	no	right	9.9	7.33
GSM550672	disomy	17	68.36	on equator	male	mixed	yes	no	yes	right	11.5	35.55
GSM550673	monosomy	nan	69.05	posterior to equator	male	epithelioid	yes	nan	no	right	13	8.34
GSM550674	disomy	10	50.17	on equator	male	epithelioid	no	yes	no	right		31.18
GSM550675	disomy	15	56.25	on equator	female	epithelioid	no	yes	no	right	11	67.38
GSM550676	monosomy	17	82.79	on equator	female	nan	no	no	no	right	13.2	31.54
GSM550677	disomy	15	70.26	on equator	male	mixed	yes	yes	no	right	13	6.18
GSM550678	monosomy	18	80.66	on equator	male	nan	no	no	no	left	11	9.3
GSM550679	monosomy	19.6	50.17	on equator	male	epithelioid	yes	yes	no	left	13.6	17.61
GSM550680	disomy	15	66.26	on equator	male	epithelioid	no	nan	no	left	10.5	31.74
GSM55068	monosomy	12	56.1	on equator	female	epithelioid	no	yes	no	left	13.7	50.46
GSM550682	monosomy	10	64.55	on equator	male	mixed	yes	yes	no	left	15	14.85
GSM550683	disomy	16	60.35	on equator	male	nan	yes	yes	yes	left	12.5	36.9
GSM550684	monosomy	20	65.72	on equator	female	mixed	yes	no	no	left	14	44.39
GSM550685	monosomy	nan	73.13	on equator	male	nan	yes	nan	no	right	13	7.59