Dataset: Expression Data from Uveal Melanoma primary tumors.

A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes...

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A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes associated with metastasis in this pathology, we studied 63 molecular profiles derived from gene expression microarrays performed from enuceated primary tumors. Metastasis free survival analysis was performed to obtain clinical and genomic variables associated to metastasis occurrence. We also compared within the 57 tumors with at least 36 months follow-up, 28 uveal melanoma from patients who developed liver metastases (meta1 group) with 29 tumors arising from patients without metastases (or later metastases, i.e. after 36 months) (meta0 group). The transcriptome of 63 uveal melanoma from enucleation of untreated patients were analyzed using Affymetrix U133plus2 Arrays.

Species:: human
Samples:: 63
Source:: E-GEOD-22138
PubMed:: 21135111
Updated:: Dec.12, 2014
Registered:: Sep.15, 2014

Factors: (via ArrayExpress)

Sample	CHROMOSOME 3 STATUS	TUMOR DIAMETER (MM)	EYE	GENDER	TUMOR CELL TYPE	METASTASIS	MONTHS TO ENDPOINT	RETINAL DETACHMENT	EXTRASCLERAL EXTENSION	TUMOR LOCATION	TUMOR THICKNESS (MM)	AGE
GSM550623	nan	nan	right	female	mixed	no	73.0	no	nan	nan	12.2	76.54
GSM550624	nan	10	left	male	epithelioid	yes	32.13	nan	nan	on equator	11.3	67.57
GSM550625	nan	20	right	male	nan	yes	0.39	yes	nan	on equator	10.9	61.82
GSM550626	disomy	15	right	male	mixed	yes	64.0	yes	yes	posterior to equator	14	46.4
GSM550627	monosomy	20	right	male	nan	no	67.81	no	nan	anterior to equator		84.99
GSM550628	disomy	nan	left	female	mixed	no	86.08	yes	no	on equator	8.3	50.64
GSM550629	disomy	11	right	male	nan	no	85.09	yes	no	on equator	10	38.67
GSM550630	monosomy	20.9	right	male	epithelioid	yes	6.14	yes	no	on equator	10.5	59.1
GSM55063	disomy	19.4	left	male	mixed	no	55.79	yes	no	on equator	13.7	52.33
GSM550632	disomy	15	right	male	mixed	no	55.23	no	no	on equator	10.1	32.94
GSM550633	monosomy	13	right	male	mixed	yes	7.92	yes	no	on equator	13.8	70.09
GSM550634	nan	15	left	male	mixed	yes	16.76	yes	nan	posterior to equator	7.5	60.8
GSM550635	monosomy	13	left	female	mixed	yes	0.92	yes	yes	on equator	12.7	54.81
GSM550636	nan	15	left	male	nan	yes	6.54	yes	no	on equator	12.4	75.66
GSM550637	partial monosomy		right	male	mixed	no	89.82	yes	no	on equator	10.4	45.97
GSM550638	monosomy	12	left	female	epithelioid	yes	21.78	no	no	on equator	10.5	51.61
GSM550639	nan		right	female	mixed	no	120.64	no	nan	nan	8.9	66.2
GSM550640	disomy	23	left	female	mixed	no	95.47	no	no	on equator	15	51.95
GSM55064	monosomy	nan	left	male	nan	no	25.13	no	no	posterior to equator	12	59.41
GSM550642	monosomy	10	left	male	nan	no	60.06	yes	no	nan	8.9	68.51
GSM550643	monosomy	16	right	male	nan	no	14.16	yes	no	on equator	13	65.62
GSM550644	disomy	17	left	female	mixed	no	67.98	yes	no	on equator	9.7	47.62
GSM550645	nan	21	right	male	mixed	yes	7.06	yes	nan	all over the eye	14	69.09
GSM550646	monosomy	12	right	female	epithelioid	yes	8.67	yes	nan	posterior and on equator	10	75.75
GSM550647	monosomy	18	left	female	nan	yes	49.02	yes	no	on equator	11.7	67.46
GSM550648	monosomy	15	left	female	nan	yes	28.88	yes	no	on equator	11.4	40.41
GSM550649	partial monosomy	22	left	male	epithelioid	yes	20.99	yes	no	nan	14	72.29
GSM550650	monosomy	13	left	male	mixed	no	100.4	no	no	on equator	13	62.62
GSM55065	partial monosomy	15	right	female	mixed	no	85.82	no	no	posterior to equator	11	51.91
GSM550652	monosomy	10	right	male	epithelioid	yes	24.54	no	no	anterior to equator	11	63.03
GSM550653	partial monosomy	nan	right	male	mixed	yes	35.78	yes	no	on equator	12.8	65.2
GSM550654	disomy	18	right	male	nan	no	55.75	yes	no	on equator	11	40.31
GSM550655	disomy	17	left	female	mixed	no	90.02	no	nan	on equator	13	28.56
GSM550656	disomy	16	left	male	nan	no	93.73	yes	no	posterior to equator	10.5	57.69
GSM550657	monosomy	19	left	female	epithelioid	yes	27.3	yes	no	on equator	11.7	55.68
GSM550658	disomy	20	left	male	mixed	no	70.14	no	no	on equator	14	72.82
GSM550659	partial monosomy	17	right	female	nan	yes	52.57	yes	nan	posterior and on equator	13.5	47.43
GSM550660	monosomy	nan	left	male	epithelioid	no	39.69	no	no	nan	11.1	78.98
GSM55066	monosomy	16	right	female	epithelioid	yes	18.96	no	no	on equator	11.7	77.95
GSM550662	monosomy	nan	left	male	epithelioid	yes	12.88	no	no	on equator	11.5	62.88
GSM550663	monosomy	10	left	female	epithelioid	yes	0.13	yes	no	on equator	9.3	54.41
GSM550664	monosomy	11	right	female	epithelioid	yes	24.44	no	no	anterior to equator	11.8	77.68
GSM550665	disomy	19	left	female	nan	no	62.69	no	no	on equator	12	56.17
GSM550666	monosomy	20	left	male	epithelioid	no	67.75	no	no	on equator	12.4	72.79
GSM550667	monosomy	16	right	female	nan	yes	68.37	nan	yes	posterior to equator		53.07
GSM550668	monosomy	12	left	male	nan	yes	14.95	yes	no	on equator	10.5	48.46
GSM550669	nan	11	right	female	epithelioid	yes	58.74	yes	no	posterior and on equator	11.5	68.83
GSM550670	monosomy	nan	left	male	mixed	yes	18.89	yes	no	posterior to equator	17	62.12
GSM55067	monosomy	nan	right	male	epithelioid	yes	7.33	yes	no	posterior to equator	9.9	56.33
GSM550672	disomy	17	right	male	mixed	yes	35.55	no	yes	on equator	11.5	68.36
GSM550673	monosomy	nan	right	male	epithelioid	yes	8.34	nan	no	posterior to equator	13	69.05
GSM550674	disomy	10	right	male	epithelioid	no	31.18	yes	no	on equator		50.17
GSM550675	disomy	15	right	female	epithelioid	no	67.38	yes	no	on equator	11	56.25
GSM550676	monosomy	17	right	female	nan	no	31.54	no	no	on equator	13.2	82.79
GSM550677	disomy	15	right	male	mixed	yes	6.18	yes	no	on equator	13	70.26
GSM550678	monosomy	18	left	male	nan	no	9.3	no	no	on equator	11	80.66
GSM550679	monosomy	19.6	left	male	epithelioid	yes	17.61	yes	no	on equator	13.6	50.17
GSM550680	disomy	15	left	male	epithelioid	no	31.74	nan	no	on equator	10.5	66.26
GSM55068	monosomy	12	left	female	epithelioid	no	50.46	yes	no	on equator	13.7	56.1
GSM550682	monosomy	10	left	male	mixed	yes	14.85	yes	no	on equator	15	64.55
GSM550683	disomy	16	left	male	nan	yes	36.9	yes	yes	on equator	12.5	60.35
GSM550684	monosomy	20	left	female	mixed	yes	44.39	no	no	on equator	14	65.72
GSM550685	monosomy	nan	right	male	nan	yes	7.59	nan	no	on equator	13	73.13