Dataset: Expression Data from Uveal Melanoma primary tumors.

A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes...

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A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes associated with metastasis in this pathology, we studied 63 molecular profiles derived from gene expression microarrays performed from enuceated primary tumors. Metastasis free survival analysis was performed to obtain clinical and genomic variables associated to metastasis occurrence. We also compared within the 57 tumors with at least 36 months follow-up, 28 uveal melanoma from patients who developed liver metastases (meta1 group) with 29 tumors arising from patients without metastases (or later metastases, i.e. after 36 months) (meta0 group). The transcriptome of 63 uveal melanoma from enucleation of untreated patients were analyzed using Affymetrix U133plus2 Arrays.

Species:: human
Samples:: 63
Source:: E-GEOD-22138
PubMed:: 21135111
Updated:: Dec.12, 2014
Registered:: Sep.15, 2014

Factors: (via ArrayExpress)

Sample	CHROMOSOME 3 STATUS	TUMOR DIAMETER (MM)	TUMOR LOCATION	GENDER	AGE	METASTASIS	RETINAL DETACHMENT	EXTRASCLERAL EXTENSION	EYE	TUMOR THICKNESS (MM)	MONTHS TO ENDPOINT	TUMOR CELL TYPE
GSM550623	nan	nan	nan	female	76.54	no	no	nan	right	12.2	73.0	mixed
GSM550624	nan	10	on equator	male	67.57	yes	nan	nan	left	11.3	32.13	epithelioid
GSM550625	nan	20	on equator	male	61.82	yes	yes	nan	right	10.9	0.39	nan
GSM550626	disomy	15	posterior to equator	male	46.4	yes	yes	yes	right	14	64.0	mixed
GSM550627	monosomy	20	anterior to equator	male	84.99	no	no	nan	right		67.81	nan
GSM550628	disomy	nan	on equator	female	50.64	no	yes	no	left	8.3	86.08	mixed
GSM550629	disomy	11	on equator	male	38.67	no	yes	no	right	10	85.09	nan
GSM550630	monosomy	20.9	on equator	male	59.1	yes	yes	no	right	10.5	6.14	epithelioid
GSM55063	disomy	19.4	on equator	male	52.33	no	yes	no	left	13.7	55.79	mixed
GSM550632	disomy	15	on equator	male	32.94	no	no	no	right	10.1	55.23	mixed
GSM550633	monosomy	13	on equator	male	70.09	yes	yes	no	right	13.8	7.92	mixed
GSM550634	nan	15	posterior to equator	male	60.8	yes	yes	nan	left	7.5	16.76	mixed
GSM550635	monosomy	13	on equator	female	54.81	yes	yes	yes	left	12.7	0.92	mixed
GSM550636	nan	15	on equator	male	75.66	yes	yes	no	left	12.4	6.54	nan
GSM550637	partial monosomy		on equator	male	45.97	no	yes	no	right	10.4	89.82	mixed
GSM550638	monosomy	12	on equator	female	51.61	yes	no	no	left	10.5	21.78	epithelioid
GSM550639	nan		nan	female	66.2	no	no	nan	right	8.9	120.64	mixed
GSM550640	disomy	23	on equator	female	51.95	no	no	no	left	15	95.47	mixed
GSM55064	monosomy	nan	posterior to equator	male	59.41	no	no	no	left	12	25.13	nan
GSM550642	monosomy	10	nan	male	68.51	no	yes	no	left	8.9	60.06	nan
GSM550643	monosomy	16	on equator	male	65.62	no	yes	no	right	13	14.16	nan
GSM550644	disomy	17	on equator	female	47.62	no	yes	no	left	9.7	67.98	mixed
GSM550645	nan	21	all over the eye	male	69.09	yes	yes	nan	right	14	7.06	mixed
GSM550646	monosomy	12	posterior and on equator	female	75.75	yes	yes	nan	right	10	8.67	epithelioid
GSM550647	monosomy	18	on equator	female	67.46	yes	yes	no	left	11.7	49.02	nan
GSM550648	monosomy	15	on equator	female	40.41	yes	yes	no	left	11.4	28.88	nan
GSM550649	partial monosomy	22	nan	male	72.29	yes	yes	no	left	14	20.99	epithelioid
GSM550650	monosomy	13	on equator	male	62.62	no	no	no	left	13	100.4	mixed
GSM55065	partial monosomy	15	posterior to equator	female	51.91	no	no	no	right	11	85.82	mixed
GSM550652	monosomy	10	anterior to equator	male	63.03	yes	no	no	right	11	24.54	epithelioid
GSM550653	partial monosomy	nan	on equator	male	65.2	yes	yes	no	right	12.8	35.78	mixed
GSM550654	disomy	18	on equator	male	40.31	no	yes	no	right	11	55.75	nan
GSM550655	disomy	17	on equator	female	28.56	no	no	nan	left	13	90.02	mixed
GSM550656	disomy	16	posterior to equator	male	57.69	no	yes	no	left	10.5	93.73	nan
GSM550657	monosomy	19	on equator	female	55.68	yes	yes	no	left	11.7	27.3	epithelioid
GSM550658	disomy	20	on equator	male	72.82	no	no	no	left	14	70.14	mixed
GSM550659	partial monosomy	17	posterior and on equator	female	47.43	yes	yes	nan	right	13.5	52.57	nan
GSM550660	monosomy	nan	nan	male	78.98	no	no	no	left	11.1	39.69	epithelioid
GSM55066	monosomy	16	on equator	female	77.95	yes	no	no	right	11.7	18.96	epithelioid
GSM550662	monosomy	nan	on equator	male	62.88	yes	no	no	left	11.5	12.88	epithelioid
GSM550663	monosomy	10	on equator	female	54.41	yes	yes	no	left	9.3	0.13	epithelioid
GSM550664	monosomy	11	anterior to equator	female	77.68	yes	no	no	right	11.8	24.44	epithelioid
GSM550665	disomy	19	on equator	female	56.17	no	no	no	left	12	62.69	nan
GSM550666	monosomy	20	on equator	male	72.79	no	no	no	left	12.4	67.75	epithelioid
GSM550667	monosomy	16	posterior to equator	female	53.07	yes	nan	yes	right		68.37	nan
GSM550668	monosomy	12	on equator	male	48.46	yes	yes	no	left	10.5	14.95	nan
GSM550669	nan	11	posterior and on equator	female	68.83	yes	yes	no	right	11.5	58.74	epithelioid
GSM550670	monosomy	nan	posterior to equator	male	62.12	yes	yes	no	left	17	18.89	mixed
GSM55067	monosomy	nan	posterior to equator	male	56.33	yes	yes	no	right	9.9	7.33	epithelioid
GSM550672	disomy	17	on equator	male	68.36	yes	no	yes	right	11.5	35.55	mixed
GSM550673	monosomy	nan	posterior to equator	male	69.05	yes	nan	no	right	13	8.34	epithelioid
GSM550674	disomy	10	on equator	male	50.17	no	yes	no	right		31.18	epithelioid
GSM550675	disomy	15	on equator	female	56.25	no	yes	no	right	11	67.38	epithelioid
GSM550676	monosomy	17	on equator	female	82.79	no	no	no	right	13.2	31.54	nan
GSM550677	disomy	15	on equator	male	70.26	yes	yes	no	right	13	6.18	mixed
GSM550678	monosomy	18	on equator	male	80.66	no	no	no	left	11	9.3	nan
GSM550679	monosomy	19.6	on equator	male	50.17	yes	yes	no	left	13.6	17.61	epithelioid
GSM550680	disomy	15	on equator	male	66.26	no	nan	no	left	10.5	31.74	epithelioid
GSM55068	monosomy	12	on equator	female	56.1	no	yes	no	left	13.7	50.46	epithelioid
GSM550682	monosomy	10	on equator	male	64.55	yes	yes	no	left	15	14.85	mixed
GSM550683	disomy	16	on equator	male	60.35	yes	yes	yes	left	12.5	36.9	nan
GSM550684	monosomy	20	on equator	female	65.72	yes	no	no	left	14	44.39	mixed
GSM550685	monosomy	nan	on equator	male	73.13	yes	nan	no	right	13	7.59	nan