Dataset: Expression Data from Uveal Melanoma primary tumors.

A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes...

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A high percentage of uveal melanoma patients develop metastatic tumors that predominately occur in the liver. To identify genes associated with metastasis in this pathology, we studied 63 molecular profiles derived from gene expression microarrays performed from enuceated primary tumors. Metastasis free survival analysis was performed to obtain clinical and genomic variables associated to metastasis occurrence. We also compared within the 57 tumors with at least 36 months follow-up, 28 uveal melanoma from patients who developed liver metastases (meta1 group) with 29 tumors arising from patients without metastases (or later metastases, i.e. after 36 months) (meta0 group). The transcriptome of 63 uveal melanoma from enucleation of untreated patients were analyzed using Affymetrix U133plus2 Arrays.

Species:: human
Samples:: 63
Source:: E-GEOD-22138
PubMed:: 21135111
Updated:: Dec.12, 2014
Registered:: Sep.15, 2014

Factors: (via ArrayExpress)

Sample	CHROMOSOME 3 STATUS	TUMOR DIAMETER (MM)	EYE	GENDER	AGE	METASTASIS	RETINAL DETACHMENT	EXTRASCLERAL EXTENSION	TUMOR LOCATION	TUMOR THICKNESS (MM)	MONTHS TO ENDPOINT	TUMOR CELL TYPE
GSM550623	nan	nan	right	female	76.54	no	no	nan	nan	12.2	73.0	mixed
GSM550624	nan	10	left	male	67.57	yes	nan	nan	on equator	11.3	32.13	epithelioid
GSM550625	nan	20	right	male	61.82	yes	yes	nan	on equator	10.9	0.39	nan
GSM550626	disomy	15	right	male	46.4	yes	yes	yes	posterior to equator	14	64.0	mixed
GSM550627	monosomy	20	right	male	84.99	no	no	nan	anterior to equator		67.81	nan
GSM550628	disomy	nan	left	female	50.64	no	yes	no	on equator	8.3	86.08	mixed
GSM550629	disomy	11	right	male	38.67	no	yes	no	on equator	10	85.09	nan
GSM550630	monosomy	20.9	right	male	59.1	yes	yes	no	on equator	10.5	6.14	epithelioid
GSM55063	disomy	19.4	left	male	52.33	no	yes	no	on equator	13.7	55.79	mixed
GSM550632	disomy	15	right	male	32.94	no	no	no	on equator	10.1	55.23	mixed
GSM550633	monosomy	13	right	male	70.09	yes	yes	no	on equator	13.8	7.92	mixed
GSM550634	nan	15	left	male	60.8	yes	yes	nan	posterior to equator	7.5	16.76	mixed
GSM550635	monosomy	13	left	female	54.81	yes	yes	yes	on equator	12.7	0.92	mixed
GSM550636	nan	15	left	male	75.66	yes	yes	no	on equator	12.4	6.54	nan
GSM550637	partial monosomy		right	male	45.97	no	yes	no	on equator	10.4	89.82	mixed
GSM550638	monosomy	12	left	female	51.61	yes	no	no	on equator	10.5	21.78	epithelioid
GSM550639	nan		right	female	66.2	no	no	nan	nan	8.9	120.64	mixed
GSM550640	disomy	23	left	female	51.95	no	no	no	on equator	15	95.47	mixed
GSM55064	monosomy	nan	left	male	59.41	no	no	no	posterior to equator	12	25.13	nan
GSM550642	monosomy	10	left	male	68.51	no	yes	no	nan	8.9	60.06	nan
GSM550643	monosomy	16	right	male	65.62	no	yes	no	on equator	13	14.16	nan
GSM550644	disomy	17	left	female	47.62	no	yes	no	on equator	9.7	67.98	mixed
GSM550645	nan	21	right	male	69.09	yes	yes	nan	all over the eye	14	7.06	mixed
GSM550646	monosomy	12	right	female	75.75	yes	yes	nan	posterior and on equator	10	8.67	epithelioid
GSM550647	monosomy	18	left	female	67.46	yes	yes	no	on equator	11.7	49.02	nan
GSM550648	monosomy	15	left	female	40.41	yes	yes	no	on equator	11.4	28.88	nan
GSM550649	partial monosomy	22	left	male	72.29	yes	yes	no	nan	14	20.99	epithelioid
GSM550650	monosomy	13	left	male	62.62	no	no	no	on equator	13	100.4	mixed
GSM55065	partial monosomy	15	right	female	51.91	no	no	no	posterior to equator	11	85.82	mixed
GSM550652	monosomy	10	right	male	63.03	yes	no	no	anterior to equator	11	24.54	epithelioid
GSM550653	partial monosomy	nan	right	male	65.2	yes	yes	no	on equator	12.8	35.78	mixed
GSM550654	disomy	18	right	male	40.31	no	yes	no	on equator	11	55.75	nan
GSM550655	disomy	17	left	female	28.56	no	no	nan	on equator	13	90.02	mixed
GSM550656	disomy	16	left	male	57.69	no	yes	no	posterior to equator	10.5	93.73	nan
GSM550657	monosomy	19	left	female	55.68	yes	yes	no	on equator	11.7	27.3	epithelioid
GSM550658	disomy	20	left	male	72.82	no	no	no	on equator	14	70.14	mixed
GSM550659	partial monosomy	17	right	female	47.43	yes	yes	nan	posterior and on equator	13.5	52.57	nan
GSM550660	monosomy	nan	left	male	78.98	no	no	no	nan	11.1	39.69	epithelioid
GSM55066	monosomy	16	right	female	77.95	yes	no	no	on equator	11.7	18.96	epithelioid
GSM550662	monosomy	nan	left	male	62.88	yes	no	no	on equator	11.5	12.88	epithelioid
GSM550663	monosomy	10	left	female	54.41	yes	yes	no	on equator	9.3	0.13	epithelioid
GSM550664	monosomy	11	right	female	77.68	yes	no	no	anterior to equator	11.8	24.44	epithelioid
GSM550665	disomy	19	left	female	56.17	no	no	no	on equator	12	62.69	nan
GSM550666	monosomy	20	left	male	72.79	no	no	no	on equator	12.4	67.75	epithelioid
GSM550667	monosomy	16	right	female	53.07	yes	nan	yes	posterior to equator		68.37	nan
GSM550668	monosomy	12	left	male	48.46	yes	yes	no	on equator	10.5	14.95	nan
GSM550669	nan	11	right	female	68.83	yes	yes	no	posterior and on equator	11.5	58.74	epithelioid
GSM550670	monosomy	nan	left	male	62.12	yes	yes	no	posterior to equator	17	18.89	mixed
GSM55067	monosomy	nan	right	male	56.33	yes	yes	no	posterior to equator	9.9	7.33	epithelioid
GSM550672	disomy	17	right	male	68.36	yes	no	yes	on equator	11.5	35.55	mixed
GSM550673	monosomy	nan	right	male	69.05	yes	nan	no	posterior to equator	13	8.34	epithelioid
GSM550674	disomy	10	right	male	50.17	no	yes	no	on equator		31.18	epithelioid
GSM550675	disomy	15	right	female	56.25	no	yes	no	on equator	11	67.38	epithelioid
GSM550676	monosomy	17	right	female	82.79	no	no	no	on equator	13.2	31.54	nan
GSM550677	disomy	15	right	male	70.26	yes	yes	no	on equator	13	6.18	mixed
GSM550678	monosomy	18	left	male	80.66	no	no	no	on equator	11	9.3	nan
GSM550679	monosomy	19.6	left	male	50.17	yes	yes	no	on equator	13.6	17.61	epithelioid
GSM550680	disomy	15	left	male	66.26	no	nan	no	on equator	10.5	31.74	epithelioid
GSM55068	monosomy	12	left	female	56.1	no	yes	no	on equator	13.7	50.46	epithelioid
GSM550682	monosomy	10	left	male	64.55	yes	yes	no	on equator	15	14.85	mixed
GSM550683	disomy	16	left	male	60.35	yes	yes	yes	on equator	12.5	36.9	nan
GSM550684	monosomy	20	left	female	65.72	yes	no	no	on equator	14	44.39	mixed
GSM550685	monosomy	nan	right	male	73.13	yes	nan	no	on equator	13	7.59	nan