Dataset: Human Nephrosclerosis Triggers a Hypoxia-Related Glomerulopathy

Expression data from microdissected glomeruli to examine the role of hypoxia in glomerulosclerosis of human Nephrosclerosis (NSC). Human Kidney biopsies of patients with NSC (n=14) and TN (n=4) were selected for RNA extraction and hybridization on Affymetrix microarrays. Gene expression data was then analysed using Genepattern and Genomatix software suites which revealed that CXCR4/CXCL12 plays a role in human NSC and therefore indicate that hypoxia contributes to glomerular damage in NSC.

Species:

human

Samples:

18

Source:

E-GEOD-20602

PubMed:

20019191

Updated:

Dec.12, 2014

Registered:

Jun.19, 2014