Dataset: Transcription profiling by array of mouse embryonic and induced pluripotent stem cells

Pluripotent cells can be derived from somatic cells by either overexpression of defined transcription factors (resulting in induced pluripotent stem cells (iPSCs)) or by nuclear transfer or cloning (resulting in NT-ESCs). To determine whether cloning further reprograms iPSCs, we used iPSCs as donor cells in nuclear transfer experiments. An iPSC clone derived from tail-tip fibroblasts using adenoviral vectors was used as donor cell in nuclear transfer experiments. RNA was isolated from both parental iPSC clone and derivative NT-ESCs lines and analyzed.

Species:

mouse

Samples:

4

Source:

E-GEOD-20575

PubMed:

20418860

Updated:

Dec.12, 2014

Registered:

Nov.11, 2014