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Home › Dataset Library › Transcription profiling by array of human Reh cells expressing shRNA targeting CBFA2T3 and/or IKKbeta(EE)

Dataset: Transcription profiling by array of human Reh cells expressing shRNA targeting CBFA2T3 and/or IKKbeta(EE)

Genome-wide gene expression analysis of Reh cells following transfection with shRNA targeting CBFA2T3, constitutively active IKKβ(EE), or...

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Genome-wide gene expression analysis of Reh cells following transfection with shRNA targeting CBFA2T3, constitutively active IKKβ(EE), or both in combination. Affymetrix U133 Plus 2.0 oligonucleotide arrays were hybridized to determine the gene expression profile of acute lymphoblastic leukemia-derived Reh cells following transfection with i) control shRNA construct, ii) shRNA construct targeting CBFA2T3, iii) a constitutively active variant of the IkB kinase β (IKKβ(EE)), or iv) shRNA targeting CBFA2T3 in combination with IKKβ(EE). All hybridizations were done in biological duplicates.

Species:
human

Samples:
8

Source:
E-GEOD-20115

PubMed:
20436485

Updated:
Dec.12, 2014

Registered:
Sep.15, 2014


Factors: (via ArrayExpress)
Sample GENOTYPE
GSM502627 control shRNA
GSM502627 control shRNA
GSM502629 CBFA2T3 shRNA
GSM502629 CBFA2T3 shRNA
GSM50263 IKKb(EE)
GSM50263 IKKb(EE)
GSM502633 CBFA2T3 shRNA, IKKb(EE)
GSM502633 CBFA2T3 shRNA, IKKb(EE)

Tags

  • acute lymphoblastic leukemia
  • genome
  • leukemia
  • lymphoblastic leukemia

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