Dataset: Transcriptome drift of FADU after expression of HIF-1a, Twist1 or Bmi1
Expression of HIF-1a or Twist1 or Bmi1 in human hypopharyngeal cancer cell line FADU results in the drift of transcriptome profile from...
Expression of HIF-1a or Twist1 or Bmi1 in human hypopharyngeal cancer cell line FADU results in the drift of transcriptome profile from an epithelial cell-like signature to a mesenchymal stem cell-like signature. Stable transfection of pHA-HIF1a(dODD), pFLAG-Twist1 or pcDNA3-Bmi1 in FADU cell and analyzed the transcriptome by cDNA microarray. FADU transfected with pcDNA3.1 empty vector was used as a control of experiment.
- Species:
- human
- Samples:
- 4
- Source:
- E-GEOD-19406
- Updated:
- Dec.12, 2014
- Registered:
- Sep.15, 2014
Factors:
(via ArrayExpress)
Sample | CELL LINE SOURCE TISSUE | TRANSFECTION |
---|---|---|
GSM482707 | primary human hypopharyngeal squamous cell carcinoma | pcDNA3.1 empty vector |
GSM482708 | primary human hypopharyngeal squamous cell carcinoma | pHA-HIF1a(dODD) |
GSM482709 | primary human hypopharyngeal squamous cell carcinoma | pFLAG-Twist1 |
GSM482710 | primary human hypopharyngeal squamous cell carcinoma p | cDNA3-Bmi1 |