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Home › Dataset Library › Transcriptome drift of FADU after expression of HIF-1a, Twist1 or Bmi1

Dataset: Transcriptome drift of FADU after expression of HIF-1a, Twist1 or Bmi1

Expression of HIF-1a or Twist1 or Bmi1 in human hypopharyngeal cancer cell line FADU results in the drift of transcriptome profile from...

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Expression of HIF-1a or Twist1 or Bmi1 in human hypopharyngeal cancer cell line FADU results in the drift of transcriptome profile from an epithelial cell-like signature to a mesenchymal stem cell-like signature. Stable transfection of pHA-HIF1a(dODD), pFLAG-Twist1 or pcDNA3-Bmi1 in FADU cell and analyzed the transcriptome by cDNA microarray. FADU transfected with pcDNA3.1 empty vector was used as a control of experiment.

Species:
human

Samples:
4

Source:
E-GEOD-19406

Updated:
Dec.12, 2014

Registered:
Sep.15, 2014


Factors: (via ArrayExpress)
Sample CELL LINE SOURCE TISSUE TRANSFECTION
GSM482707 primary human hypopharyngeal squamous cell carcinoma pcDNA3.1 empty vector
GSM482708 primary human hypopharyngeal squamous cell carcinoma pHA-HIF1a(dODD)
GSM482709 primary human hypopharyngeal squamous cell carcinoma pFLAG-Twist1
GSM482710 primary human hypopharyngeal squamous cell carcinoma p cDNA3-Bmi1

Tags

  • cancer
  • cell
  • epithelial cell
  • hypopharyngeal cancer
  • line
  • stem cell

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