Dataset: Transcription profiling of mouse NIH 3T3 cells, cells treated with cytochalasin D, and cells treated with latrunculin B and cytochalasin D - G-actin switch

We analysed the G-actin regulated transcriptome by gene expression analysis using previously characterised actin binding drugs. We found many known MAL/MRTF-dependent target genes of serum response factor (SRF) as well as unknown directly regulated genes. Experiment Overall Design: Three conditions were used for the microarray analysis: control NIH 3T3 cells, cells treated with cytochalasin D, and cells treated with latrunculin B and cytochalasin D. For each condition, three independent biological replicates were analysed.

Species:

mouse

Samples:

9

Source:

E-GEOD-17105

Updated:

Dec.12, 2014

Registered:

Nov.11, 2014