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Home › Dataset Library › Expression profiling of sox11-expressing glioma-initiating cell-like cells

Dataset: Expression profiling of sox11-expressing glioma-initiating cell-like cells

To identify factors involved in tumorigenicity of glioma-initiating cells (GICs), we compared gene expression in GIC-like cells with and...

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To identify factors involved in tumorigenicity of glioma-initiating cells (GICs), we compared gene expression in GIC-like cells with and without sox11 expression. We established sox11-expressing mouse glioma-initiating cell (GIC)-like cell line (NSCL61s), NSCL61s-sox11, which lost tumorigenicity when transplanted in vivo. We think that genes, which are differently expressed between NSCL61s and NSCL61s-sox11, would be new targets for glioma therapy.

Species:
mouse

Samples:
4

Source:
E-GEOD-17076

PubMed:
19808959

Updated:
Dec.12, 2014

Registered:
Nov.11, 2014


Factors: (via ArrayExpress)
Sample GENOME/VARIATION CELL LINE
GSM427234 p53-/- NSCL61
GSM427234 p53-/- NSCL61
GSM427236 p53-/-, sox11-expressing NSCL61-sox11
GSM427236 p53-/-, sox11-expressing NSCL61-sox11

Tags

  • cell
  • glioma
  • line

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