Dataset: Expression profiling of sox11-expressing glioma-initiating cell-like cells
To identify factors involved in tumorigenicity of glioma-initiating cells (GICs), we compared gene expression in GIC-like cells with and...
To identify factors involved in tumorigenicity of glioma-initiating cells (GICs), we compared gene expression in GIC-like cells with and without sox11 expression. We established sox11-expressing mouse glioma-initiating cell (GIC)-like cell line (NSCL61s), NSCL61s-sox11, which lost tumorigenicity when transplanted in vivo. We think that genes, which are differently expressed between NSCL61s and NSCL61s-sox11, would be new targets for glioma therapy.
- Species:
- mouse
- Samples:
- 4
- Source:
- E-GEOD-17076
- PubMed:
- 19808959
- Updated:
- Dec.12, 2014
- Registered:
- Nov.11, 2014
Factors:
(via ArrayExpress)
Sample | GENOME/VARIATION | CELL LINE |
---|---|---|
GSM427234 | p53-/- | NSCL61 |
GSM427234 | p53-/- | NSCL61 |
GSM427236 | p53-/-, sox11-expressing | NSCL61-sox11 |
GSM427236 | p53-/-, sox11-expressing | NSCL61-sox11 |