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Home › Dataset Library › Long-term effect on the transcriptome of loss of Frizzled4 signaling in cerebellar endothelial cells

Dataset: Long-term effect on the transcriptome of loss of Frizzled4 signaling in cerebellar endothelial cells

Transcriptional profiles of the cerebellar endothelial cells from P16 Fz4-/- animals were compared to their wild type littermate...

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Transcriptional profiles of the cerebellar endothelial cells from P16 Fz4-/- animals were compared to their wild type littermate controls. The goal is to characterize the long-term effect on the transcriptome of loss of Fz4 signaling in cerebellar endothelial cells. Endothelial cells were immuno-purification from P16 cerebellum using anti-PECAM antibody coated dynabeads. The cell immuno-purification procedure follows that described by Matsubara et al. (2000) and Su et al. (2003). 3 replicates of both wild type and Fz4-/- cerebellar endothelial cells were analyzed.

Species:
mouse

Samples:
6

Source:
E-GEOD-16707

PubMed:
19837032

Updated:
Dec.12, 2014

Registered:
Nov.11, 2014


Factors: (via ArrayExpress)
Sample GENETIC MODIFICATION
GSM418606 P16 Fz4-/-
GSM418606 P16 Fz4-/-
GSM418606 P16 Fz4-/-
GSM41862 P16 wild type
GSM41862 P16 wild type
GSM41862 P16 wild type

Tags

  • cell
  • cerebellum

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