Dataset: Transcription profiling by array of human CD4+ T cells from HIV-resistant and HIV-susceptible individuals

Understanding why some indidivual resist HIV-1 infection despite continued exposure is an important goal for vaccine development. We compared CD4+ T cell gene expression at baseline in HIV-1 resistant commercial sex-workers from Nairobi, Kenya to HIV-1 high-risk negative (non-resistant) commercial sex-workers using gene expression arrays Experiment Overall Design: CD4+ T cells from both HIV resistant and HIV low-risk negative individuals were isolated from PBMC after 24 hours of culture by negative slelction. Total RNA was isolated and gene expression compared using Affymetrix total genome arrays.

Species:

human

Samples:

18

Source:

E-GEOD-14278

Updated:

Dec.12, 2014

Registered:

Sep.11, 2014