Dataset: Transcription profiling by array of human breast cancer cell lines after treatment with miR-221/222 mimics or inhibitors
mRNA breast cancer cell lines were profiled to study the function of hsa-mir-221 and hsa-mir-222. MCF7 cell lines were profiled after...
mRNA breast cancer cell lines were profiled to study the function of hsa-mir-221 and hsa-mir-222. MCF7 cell lines were profiled after treatment with mir-221/222 mimics, and compared to profiles with transfection controls. Similarly, MDA-MB-231 cell lines were profiled after treatment with mir-221/222 inhibitors, and compared to profiles with transfection controls. Since ESR1 is a predicted target of mir-221/222 we also profiled MCF7 cell lines after disrupting ESR1 with an siRNA. Other breast cancer cell lines are provided because all cell lines were normalized together. Experiment Overall Design: mRNA breast cancer cell line profiles with some samples in duplicate or triplicate. See summary for more information.
- Species:
- human
- Samples:
- 112
- Source:
- E-GEOD-10890
- Updated:
- Dec.12, 2014
- Registered:
- Sep.03, 2014
Factors:
(via ArrayExpress)
| Sample | cell line | time | compound |
|---|---|---|---|
| GSE10890GSM275974 | BT549 | 0 | none |
| GSE10890GSM275975 | CAL851 | 0 | none |
| GSE10890GSM275976 | MDA175 | 0 | none |
| GSE10890GSM275977 | HS578T | 0 | none |
| GSE10890GSM275978 | MCF7 | 0 | none |
| GSE10890GSM275979 | BT483 | 0 | none |
| GSE10890GSM275980 | EFM192A | 0 | none |
| GSE10890GSM275981 | KPL1 | 0 | none |
| GSE10890GSM275981 | KPL1 | 0 | none |
| GSE10890GSM275983 | SKBR3 | 0 | none |
| GSE10890GSM275984 | CAL51 | 0 | none |
| GSE10890GSM275984 | CAL51 | 0 | none |
| GSE10890GSM275986 | MDA436 | 0 | none |
| GSE10890GSM275987 | CAL120 | 0 | none |
| GSE10890GSM275988 | MDA435 | 0 | none |
| GSE10890GSM275988 | MDA435 | 0 | none |
| GSE10890GSM275990 | EVSA1 | 0 | none |
| GSE10890GSM275991 | T47D | 0 | none |
| GSE10890GSM275991 | T47D | 0 | none |
| GSE10890GSM275993 | MDA231 | 0 | none |
| GSE10890GSM275994 | MDA468 | 0 | none |
| GSE10890GSM275995 | MCF10A | 0 | none |
| GSE10890GSM275995 | MCF10A | 0 | none |
| GSE10890GSM275997 | HCC1937 | 0 | none |
| GSE10890GSM275998 | MDA361 | 0 | none |
| GSE10890GSM275999 | MT3 | 0 | none |
| GSE10890GSM276000 | BT474EI | 0 | none |
| GSE10890GSM276000 | BT474EI | 0 | none |
| GSE10890GSM276000 | BT474EI | 0 | none |
| GSE10890GSM276003 | MDAMB453 | 0 | none |
| GSE10890GSM276004 | BT474 | 0 | none |
| GSE10890GSM276005 | AU565 | 0 | none |
| GSE10890GSM276006 | DU4475 | 0 | none |
| GSE10890GSM276007 | MDAMB415 | 0 | none |
| GSE10890GSM276008 | ZR751 | 0 | none |
| GSE10890GSM276009 | MDAMB468 | 0 | none |
| GSE10890GSM276010 | EFM19 | 0 | none |
| GSE10890GSM276011 | CAMA1 | 0 | none |
| GSE10890GSM276012 | HCC1419 | 0 | none |
| GSE10890GSM276013 | HCC70 | 0 | none |
| GSE10890GSM276014 | BT5491 | 0 | none |
| GSE10890GSM276015 | SKBR31 | 0 | none |
| GSE10890GSM276016 | T47D1 | 0 | none |
| GSE10890GSM276017 | CAL1201 | 0 | none |
| GSE10890GSM276018 | HCC1428 | 0 | none |
| GSE10890GSM276019 | HCC1954 | 0 | none |
| GSE10890GSM276020 | HCC2218 | 0 | none |
| GSE10890GSM276021 | HCC1500 | 0 | none |
| GSE10890GSM276022 | HCC1395 | 0 | none |
| GSE10890GSM276023 | HCC1143 | 0 | none |
| GSE10890GSM276024 | HDQP1 | 0 | none |
| GSE10890GSM276025 | ZR75 | 0 | none |
| GSE10890GSM276026 | MFM223 | 0 | none |
| GSE10890GSM276027 | HCC1569 | 0 | none |
| GSE10890GSM276028 | HCC38 | 0 | none |
| GSE10890GSM276029 | HCC1806 | 0 | none |
| GSE10890GSM276030 | CAL148 | 0 | none |
| GSE10890GSM276031 | JIMT1 | 0 | none |
| GSE10890GSM276032 | UACC812 | 0 | none |
| GSE10890GSM276033 | UACC893 | 0 | none |
| GSE10890GSM276034 | BT474.tb | 0 | none |
| GSE10890GSM276035 | MDAMB361.1 | 0 | none |
| GSE10890GSM276036 | SW527 | 0 | none |
| GSE10890GSM276037 | MDA-MB231 | 0 | none |
| GSE10890GSM276037 | MDA-MB231 | 0 | none |
| GSE10890GSM276037 | MDA-MB231 | 0 | none |
| GSE10890GSM276040 | MDA-MB231 | 18 | control for mir-221/222 inhibitor |
| GSE10890GSM276040 | MDA-MB231 | 18 | control for mir-221/222 inhibitor |
| GSE10890GSM276040 | MDA-MB231 | 18 | control for mir-221/222 inhibitor |
| GSE10890GSM276043 | MDA-MB231 | 18 | mir-221/222 inhibitor |
| GSE10890GSM276043 | MDA-MB231 | 18 | mir-221/222 inhibitor |
| GSE10890GSM276043 | MDA-MB231 | 18 | mir-221/222 inhibitor |
| GSE10890GSM275978 | MCF7 | 0 | none |
| GSE10890GSM275978 | MCF7 | 0 | none |
| GSE10890GSM275978 | MCF7 | 0 | none |
| GSE10890GSM276049 | MCF7 | 18 | control for mir-221/222 mimic |
| GSE10890GSM276049 | MCF7 | 18 | control for mir-221/222 mimic |
| GSE10890GSM276049 | MCF7 | 18 | control for mir-221/222 mimic |
| GSE10890GSM276052 | MCF7 | 18 | mir-221/222 mimic |
| GSE10890GSM276052 | MCF7 | 18 | mir-221/222 mimic |
| GSE10890GSM276052 | MCF7 | 18 | mir-221/222 mimic |
| GSE10890GSM276055 | MCF7 | 18 | ESR1 siRNA control |
| GSE10890GSM276055 | MCF7 | 18 | ESR1 siRNA control |
| GSE10890GSM276055 | MCF7 | 18 | ESR1 siRNA control |
| GSE10890GSM276058 | MCF7 | 18 | ESR1 siRNA |
| GSE10890GSM276058 | MCF7 | 18 | ESR1 siRNA |
| GSE10890GSM276004 | BT474 | 0 | none |
| GSE10890GSM276004 | BT474 | 0 | none |
| GSE10890GSM276062 | MDA-MB231 | 72 | none |
| GSE10890GSM276062 | MDA-MB231 | 72 | none |
| GSE10890GSM276062 | MDA-MB231 | 72 | none |
| GSE10890GSM276065 | MDA-MB231 | 72 | control for mir-221/222 inhibitor |
| GSE10890GSM276065 | MDA-MB231 | 72 | control for mir-221/222 inhibitor |
| GSE10890GSM276067 | MDA-MB231 | 72 | control for mir-221/222 inhibitor |
| GSE10890GSM276068 | MDA-MB231 | 72 | mir-221/222 inhibitor |
| GSE10890GSM276068 | MDA-MB231 | 72 | mir-221/222 inhibitor |
| GSE10890GSM276068 | MDA-MB231 | 72 | mir-221/222 inhibitor |
| GSE10890GSM276071 | MCF7 | 72 | none |
| GSE10890GSM276071 | MCF7 | 72 | none |
| GSE10890GSM276071 | MCF7 | 72 | none |
| GSE10890GSM276074 | MCF7 | 72 | control for mir-221/222 mimic |
| GSE10890GSM276074 | MCF7 | 72 | control for mir-221/222 mimic |
| GSE10890GSM276074 | MCF7 | 72 | control for mir-221/222 mimic |
| GSE10890GSM276077 | MCF7 | 72 | mir-221/222 mimic |
| GSE10890GSM276077 | MCF7 | 72 | mir-221/222 mimic |
| GSE10890GSM276077 | MCF7 | 72 | mir-221/222 mimic |
| GSE10890GSM276080 | MCF7 | 72 | control for ESR1 siRNA |
| GSE10890GSM276080 | MCF7 | 72 | control for ESR1 siRNA |
| GSE10890GSM276080 | MCF7 | 72 | control for ESR1 siRNA |
| GSE10890GSM276083 | MCF7 | 72 | ESR1 siRNA |
| GSE10890GSM276083 | MCF7 | 72 | ESR1 siRNA |
| GSE10890GSM276083 | MCF7 | 72 | ESR1 siRNA |