Dataset: Transcription profiling by array of human breast cancer cell lines after treatment with miR-221/222 mimics or inhibitors

mRNA breast cancer cell lines were profiled to study the function of hsa-mir-221 and hsa-mir-222. MCF7 cell lines were profiled after...

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mRNA breast cancer cell lines were profiled to study the function of hsa-mir-221 and hsa-mir-222. MCF7 cell lines were profiled after treatment with mir-221/222 mimics, and compared to profiles with transfection controls. Similarly, MDA-MB-231 cell lines were profiled after treatment with mir-221/222 inhibitors, and compared to profiles with transfection controls. Since ESR1 is a predicted target of mir-221/222 we also profiled MCF7 cell lines after disrupting ESR1 with an siRNA. Other breast cancer cell lines are provided because all cell lines were normalized together. Experiment Overall Design: mRNA breast cancer cell line profiles with some samples in duplicate or triplicate. See summary for more information.

Species:: human
Samples:: 112
Source:: E-GEOD-10890
Updated:: Dec.12, 2014
Registered:: Sep.03, 2014

Factors: (via ArrayExpress)

Sample	time	cell line	compound
GSE10890GSM275974	0	BT549	none
GSE10890GSM275975	0	CAL851	none
GSE10890GSM275976	0	MDA175	none
GSE10890GSM275977	0	HS578T	none
GSE10890GSM275978	0	MCF7	none
GSE10890GSM275979	0	BT483	none
GSE10890GSM275980	0	EFM192A	none
GSE10890GSM275981	0	KPL1	none
GSE10890GSM275981	0	KPL1	none
GSE10890GSM275983	0	SKBR3	none
GSE10890GSM275984	0	CAL51	none
GSE10890GSM275984	0	CAL51	none
GSE10890GSM275986	0	MDA436	none
GSE10890GSM275987	0	CAL120	none
GSE10890GSM275988	0	MDA435	none
GSE10890GSM275988	0	MDA435	none
GSE10890GSM275990	0	EVSA1	none
GSE10890GSM275991	0	T47D	none
GSE10890GSM275991	0	T47D	none
GSE10890GSM275993	0	MDA231	none
GSE10890GSM275994	0	MDA468	none
GSE10890GSM275995	0	MCF10A	none
GSE10890GSM275995	0	MCF10A	none
GSE10890GSM275997	0	HCC1937	none
GSE10890GSM275998	0	MDA361	none
GSE10890GSM275999	0	MT3	none
GSE10890GSM276000	0	BT474EI	none
GSE10890GSM276000	0	BT474EI	none
GSE10890GSM276000	0	BT474EI	none
GSE10890GSM276003	0	MDAMB453	none
GSE10890GSM276004	0	BT474	none
GSE10890GSM276005	0	AU565	none
GSE10890GSM276006	0	DU4475	none
GSE10890GSM276007	0	MDAMB415	none
GSE10890GSM276008	0	ZR751	none
GSE10890GSM276009	0	MDAMB468	none
GSE10890GSM276010	0	EFM19	none
GSE10890GSM276011	0	CAMA1	none
GSE10890GSM276012	0	HCC1419	none
GSE10890GSM276013	0	HCC70	none
GSE10890GSM276014	0	BT5491	none
GSE10890GSM276015	0	SKBR31	none
GSE10890GSM276016	0	T47D1	none
GSE10890GSM276017	0	CAL1201	none
GSE10890GSM276018	0	HCC1428	none
GSE10890GSM276019	0	HCC1954	none
GSE10890GSM276020	0	HCC2218	none
GSE10890GSM276021	0	HCC1500	none
GSE10890GSM276022	0	HCC1395	none
GSE10890GSM276023	0	HCC1143	none
GSE10890GSM276024	0	HDQP1	none
GSE10890GSM276025	0	ZR75	none
GSE10890GSM276026	0	MFM223	none
GSE10890GSM276027	0	HCC1569	none
GSE10890GSM276028	0	HCC38	none
GSE10890GSM276029	0	HCC1806	none
GSE10890GSM276030	0	CAL148	none
GSE10890GSM276031	0	JIMT1	none
GSE10890GSM276032	0	UACC812	none
GSE10890GSM276033	0	UACC893	none
GSE10890GSM276034	0	BT474.tb	none
GSE10890GSM276035	0	MDAMB361.1	none
GSE10890GSM276036	0	SW527	none
GSE10890GSM276037	0	MDA-MB231	none
GSE10890GSM276037	0	MDA-MB231	none
GSE10890GSM276037	0	MDA-MB231	none
GSE10890GSM276040	18	MDA-MB231	control for mir-221/222 inhibitor
GSE10890GSM276040	18	MDA-MB231	control for mir-221/222 inhibitor
GSE10890GSM276040	18	MDA-MB231	control for mir-221/222 inhibitor
GSE10890GSM276043	18	MDA-MB231	mir-221/222 inhibitor
GSE10890GSM276043	18	MDA-MB231	mir-221/222 inhibitor
GSE10890GSM276043	18	MDA-MB231	mir-221/222 inhibitor
GSE10890GSM275978	0	MCF7	none
GSE10890GSM275978	0	MCF7	none
GSE10890GSM275978	0	MCF7	none
GSE10890GSM276049	18	MCF7	control for mir-221/222 mimic
GSE10890GSM276049	18	MCF7	control for mir-221/222 mimic
GSE10890GSM276049	18	MCF7	control for mir-221/222 mimic
GSE10890GSM276052	18	MCF7	mir-221/222 mimic
GSE10890GSM276052	18	MCF7	mir-221/222 mimic
GSE10890GSM276052	18	MCF7	mir-221/222 mimic
GSE10890GSM276055	18	MCF7	ESR1 siRNA control
GSE10890GSM276055	18	MCF7	ESR1 siRNA control
GSE10890GSM276055	18	MCF7	ESR1 siRNA control
GSE10890GSM276058	18	MCF7	ESR1 siRNA
GSE10890GSM276058	18	MCF7	ESR1 siRNA
GSE10890GSM276004	0	BT474	none
GSE10890GSM276004	0	BT474	none
GSE10890GSM276062	72	MDA-MB231	none
GSE10890GSM276062	72	MDA-MB231	none
GSE10890GSM276062	72	MDA-MB231	none
GSE10890GSM276065	72	MDA-MB231	control for mir-221/222 inhibitor
GSE10890GSM276065	72	MDA-MB231	control for mir-221/222 inhibitor
GSE10890GSM276067	72	MDA-MB231	control for mir-221/222 inhibitor
GSE10890GSM276068	72	MDA-MB231	mir-221/222 inhibitor
GSE10890GSM276068	72	MDA-MB231	mir-221/222 inhibitor
GSE10890GSM276068	72	MDA-MB231	mir-221/222 inhibitor
GSE10890GSM276071	72	MCF7	none
GSE10890GSM276071	72	MCF7	none
GSE10890GSM276071	72	MCF7	none
GSE10890GSM276074	72	MCF7	control for mir-221/222 mimic
GSE10890GSM276074	72	MCF7	control for mir-221/222 mimic
GSE10890GSM276074	72	MCF7	control for mir-221/222 mimic
GSE10890GSM276077	72	MCF7	mir-221/222 mimic
GSE10890GSM276077	72	MCF7	mir-221/222 mimic
GSE10890GSM276077	72	MCF7	mir-221/222 mimic
GSE10890GSM276080	72	MCF7	control for ESR1 siRNA
GSE10890GSM276080	72	MCF7	control for ESR1 siRNA
GSE10890GSM276080	72	MCF7	control for ESR1 siRNA
GSE10890GSM276083	72	MCF7	ESR1 siRNA
GSE10890GSM276083	72	MCF7	ESR1 siRNA
GSE10890GSM276083	72	MCF7	ESR1 siRNA