Dataset: Transcription profiling by array of human breast cancer cell lines after treatment with miR-221/222 mimics or inhibitors
mRNA breast cancer cell lines were profiled to study the function of hsa-mir-221 and hsa-mir-222. MCF7 cell lines were profiled after...
mRNA breast cancer cell lines were profiled to study the function of hsa-mir-221 and hsa-mir-222. MCF7 cell lines were profiled after treatment with mir-221/222 mimics, and compared to profiles with transfection controls. Similarly, MDA-MB-231 cell lines were profiled after treatment with mir-221/222 inhibitors, and compared to profiles with transfection controls. Since ESR1 is a predicted target of mir-221/222 we also profiled MCF7 cell lines after disrupting ESR1 with an siRNA. Other breast cancer cell lines are provided because all cell lines were normalized together. Experiment Overall Design: mRNA breast cancer cell line profiles with some samples in duplicate or triplicate. See summary for more information.
- Species:
- human
- Samples:
- 112
- Source:
- E-GEOD-10890
- Updated:
- Dec.12, 2014
- Registered:
- Sep.03, 2014
Factors:
(via ArrayExpress)
| Sample | compound | cell line | time |
|---|---|---|---|
| GSE10890GSM275974 | none | BT549 | 0 |
| GSE10890GSM275975 | none | CAL851 | 0 |
| GSE10890GSM275976 | none | MDA175 | 0 |
| GSE10890GSM275977 | none | HS578T | 0 |
| GSE10890GSM275978 | none | MCF7 | 0 |
| GSE10890GSM275979 | none | BT483 | 0 |
| GSE10890GSM275980 | none | EFM192A | 0 |
| GSE10890GSM275981 | none | KPL1 | 0 |
| GSE10890GSM275981 | none | KPL1 | 0 |
| GSE10890GSM275983 | none | SKBR3 | 0 |
| GSE10890GSM275984 | none | CAL51 | 0 |
| GSE10890GSM275984 | none | CAL51 | 0 |
| GSE10890GSM275986 | none | MDA436 | 0 |
| GSE10890GSM275987 | none | CAL120 | 0 |
| GSE10890GSM275988 | none | MDA435 | 0 |
| GSE10890GSM275988 | none | MDA435 | 0 |
| GSE10890GSM275990 | none | EVSA1 | 0 |
| GSE10890GSM275991 | none | T47D | 0 |
| GSE10890GSM275991 | none | T47D | 0 |
| GSE10890GSM275993 | none | MDA231 | 0 |
| GSE10890GSM275994 | none | MDA468 | 0 |
| GSE10890GSM275995 | none | MCF10A | 0 |
| GSE10890GSM275995 | none | MCF10A | 0 |
| GSE10890GSM275997 | none | HCC1937 | 0 |
| GSE10890GSM275998 | none | MDA361 | 0 |
| GSE10890GSM275999 | none | MT3 | 0 |
| GSE10890GSM276000 | none | BT474EI | 0 |
| GSE10890GSM276000 | none | BT474EI | 0 |
| GSE10890GSM276000 | none | BT474EI | 0 |
| GSE10890GSM276003 | none | MDAMB453 | 0 |
| GSE10890GSM276004 | none | BT474 | 0 |
| GSE10890GSM276005 | none | AU565 | 0 |
| GSE10890GSM276006 | none | DU4475 | 0 |
| GSE10890GSM276007 | none | MDAMB415 | 0 |
| GSE10890GSM276008 | none | ZR751 | 0 |
| GSE10890GSM276009 | none | MDAMB468 | 0 |
| GSE10890GSM276010 | none | EFM19 | 0 |
| GSE10890GSM276011 | none | CAMA1 | 0 |
| GSE10890GSM276012 | none | HCC1419 | 0 |
| GSE10890GSM276013 | none | HCC70 | 0 |
| GSE10890GSM276014 | none | BT5491 | 0 |
| GSE10890GSM276015 | none | SKBR31 | 0 |
| GSE10890GSM276016 | none | T47D1 | 0 |
| GSE10890GSM276017 | none | CAL1201 | 0 |
| GSE10890GSM276018 | none | HCC1428 | 0 |
| GSE10890GSM276019 | none | HCC1954 | 0 |
| GSE10890GSM276020 | none | HCC2218 | 0 |
| GSE10890GSM276021 | none | HCC1500 | 0 |
| GSE10890GSM276022 | none | HCC1395 | 0 |
| GSE10890GSM276023 | none | HCC1143 | 0 |
| GSE10890GSM276024 | none | HDQP1 | 0 |
| GSE10890GSM276025 | none | ZR75 | 0 |
| GSE10890GSM276026 | none | MFM223 | 0 |
| GSE10890GSM276027 | none | HCC1569 | 0 |
| GSE10890GSM276028 | none | HCC38 | 0 |
| GSE10890GSM276029 | none | HCC1806 | 0 |
| GSE10890GSM276030 | none | CAL148 | 0 |
| GSE10890GSM276031 | none | JIMT1 | 0 |
| GSE10890GSM276032 | none | UACC812 | 0 |
| GSE10890GSM276033 | none | UACC893 | 0 |
| GSE10890GSM276034 | none | BT474.tb | 0 |
| GSE10890GSM276035 | none | MDAMB361.1 | 0 |
| GSE10890GSM276036 | none | SW527 | 0 |
| GSE10890GSM276037 | none | MDA-MB231 | 0 |
| GSE10890GSM276037 | none | MDA-MB231 | 0 |
| GSE10890GSM276037 | none | MDA-MB231 | 0 |
| GSE10890GSM276040 | control for mir-221/222 inhibitor | MDA-MB231 | 18 |
| GSE10890GSM276040 | control for mir-221/222 inhibitor | MDA-MB231 | 18 |
| GSE10890GSM276040 | control for mir-221/222 inhibitor | MDA-MB231 | 18 |
| GSE10890GSM276043 | mir-221/222 inhibitor | MDA-MB231 | 18 |
| GSE10890GSM276043 | mir-221/222 inhibitor | MDA-MB231 | 18 |
| GSE10890GSM276043 | mir-221/222 inhibitor | MDA-MB231 | 18 |
| GSE10890GSM275978 | none | MCF7 | 0 |
| GSE10890GSM275978 | none | MCF7 | 0 |
| GSE10890GSM275978 | none | MCF7 | 0 |
| GSE10890GSM276049 | control for mir-221/222 mimic | MCF7 | 18 |
| GSE10890GSM276049 | control for mir-221/222 mimic | MCF7 | 18 |
| GSE10890GSM276049 | control for mir-221/222 mimic | MCF7 | 18 |
| GSE10890GSM276052 | mir-221/222 mimic | MCF7 | 18 |
| GSE10890GSM276052 | mir-221/222 mimic | MCF7 | 18 |
| GSE10890GSM276052 | mir-221/222 mimic | MCF7 | 18 |
| GSE10890GSM276055 | ESR1 siRNA control | MCF7 | 18 |
| GSE10890GSM276055 | ESR1 siRNA control | MCF7 | 18 |
| GSE10890GSM276055 | ESR1 siRNA control | MCF7 | 18 |
| GSE10890GSM276058 | ESR1 siRNA | MCF7 | 18 |
| GSE10890GSM276058 | ESR1 siRNA | MCF7 | 18 |
| GSE10890GSM276004 | none | BT474 | 0 |
| GSE10890GSM276004 | none | BT474 | 0 |
| GSE10890GSM276062 | none | MDA-MB231 | 72 |
| GSE10890GSM276062 | none | MDA-MB231 | 72 |
| GSE10890GSM276062 | none | MDA-MB231 | 72 |
| GSE10890GSM276065 | control for mir-221/222 inhibitor | MDA-MB231 | 72 |
| GSE10890GSM276065 | control for mir-221/222 inhibitor | MDA-MB231 | 72 |
| GSE10890GSM276067 | control for mir-221/222 inhibitor | MDA-MB231 | 72 |
| GSE10890GSM276068 | mir-221/222 inhibitor | MDA-MB231 | 72 |
| GSE10890GSM276068 | mir-221/222 inhibitor | MDA-MB231 | 72 |
| GSE10890GSM276068 | mir-221/222 inhibitor | MDA-MB231 | 72 |
| GSE10890GSM276071 | none | MCF7 | 72 |
| GSE10890GSM276071 | none | MCF7 | 72 |
| GSE10890GSM276071 | none | MCF7 | 72 |
| GSE10890GSM276074 | control for mir-221/222 mimic | MCF7 | 72 |
| GSE10890GSM276074 | control for mir-221/222 mimic | MCF7 | 72 |
| GSE10890GSM276074 | control for mir-221/222 mimic | MCF7 | 72 |
| GSE10890GSM276077 | mir-221/222 mimic | MCF7 | 72 |
| GSE10890GSM276077 | mir-221/222 mimic | MCF7 | 72 |
| GSE10890GSM276077 | mir-221/222 mimic | MCF7 | 72 |
| GSE10890GSM276080 | control for ESR1 siRNA | MCF7 | 72 |
| GSE10890GSM276080 | control for ESR1 siRNA | MCF7 | 72 |
| GSE10890GSM276080 | control for ESR1 siRNA | MCF7 | 72 |
| GSE10890GSM276083 | ESR1 siRNA | MCF7 | 72 |
| GSE10890GSM276083 | ESR1 siRNA | MCF7 | 72 |
| GSE10890GSM276083 | ESR1 siRNA | MCF7 | 72 |