Dataset: Role of SRF in activity-regulated transcription in the striatum of the brain
Ablation of the Srf gene in dopaminoceptive neurons of the brain was performed using the Cre/loxP system, with the recombinase expressed...
Ablation of the Srf gene in dopaminoceptive neurons of the brain was performed using the Cre/loxP system, with the recombinase expressed from a BAC-derived Drd1a promoter. Our goal was to analyze how loss of SRF will affect acitivity-regulated transcription induced by strong stimulation, i.e. cocaine. Keywords: Treatment x Genotype Animals were injected i.p. with either 25 mg/kg cocaine or saline and sacrificed after one hour by cervical dislocation. Expression profiling was performed using total RNA isolated from the striatum.
- Species:
- mouse
- Samples:
- 12
- Source:
- E-GEOD-10870
- Updated:
- Dec.12, 2014
- Registered:
- Nov.24, 2014
Factors:
(via ArrayExpress)
| Sample |
|---|
| GSM275526 1 |
| GSM275527 1 |
| GSM275528 1 |
| GSM275529 1 |
| GSM275530 1 |
| GSM275531 1 |
| GSM275532 1 |
| GSM275533 1 |
| GSM275534 1 |
| GSM275535 1 |
| GSM275536 1 |
| GSM275537 1 |