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Home › Dataset Library › Transcription profiling by array of human LMP1 transfected CD10-positive germinal center B cells

Dataset: Transcription profiling by array of human LMP1 transfected CD10-positive germinal center B cells

In this study, we have investigated the effect of LMP1 on gene expression in normal human GC B cells using a non-viral vector based...

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In this study, we have investigated the effect of LMP1 on gene expression in normal human GC B cells using a non-viral vector based system Experiment Overall Design: Gene expression was compared between LMP1-transfected and control vector-transfected GC B cells from three patients. RNA from the FACS-sorted transfected GC B cells was amplified. 10ug of fragmented cRNA was hybridized to HG-U133 Plus 2.0 microarrays. Differentially expressed genes were identified using significance analysis of microarrays (SAM) with a 1.5 fold change threshold and the q-value threshold set to 5%.

Species:
human

Samples:
6

Source:
E-GEOD-10821

PubMed:
18566961

Updated:
Dec.12, 2014

Registered:
Aug.12, 2014


Factors: (via ArrayExpress)
Sample genotype
GSE10821GSM273009 LMP1
GSE10821GSM273009 LMP1
GSE10821GSM273009 LMP1
GSE10821GSM272994 empty vector
GSE10821GSM272994 empty vector
GSE10821GSM272994 empty vector

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