Dataset: Effect of an AhR-/- on transcription in CD4 T cells from the spleen.
CD4+ T cells from 8-12 week female mice were isolated from wt and AhR-/- mice 24h after injection of 10µg/kg TCDD or solvent control....
CD4+ T cells from 8-12 week female mice were isolated from wt and AhR-/- mice 24h after injection of 10µg/kg TCDD or solvent control. Keywords: TCDD, AHR, immunosuppression Each experiment was performed in biological duplicates from 4 pooled animals. Since TCDD treatment showed only marginal impact on the gene expression (~10 transcripts effected in wt mice) wt - ko comparisons were performed on pooled profiles from TCDD and solvent mice.
- Species:
- mouse
- Samples:
- 8
- Source:
- E-GEOD-10084
- PubMed:
- 16972790
- Updated:
- Dec.12, 2014
- Registered:
- Nov.23, 2014
Factors:
(via ArrayExpress)
| Sample | TREATMENT | STRAIN OR LINE |
|---|---|---|
| GSM254808 | i.p. 10 �g/kg TCDD 24h prior to sacrifice | AHR ko backcrossed to C57BL/6 |
| GSM254809 | i.p. DMSO 24h prior to sacrifice | AHR ko backcrossed to C57BL/6 |
| GSM254808 | i.p. 10 �g/kg TCDD 24h prior to sacrifice | AHR ko backcrossed to C57BL/6 |
| GSM254809 | i.p. DMSO 24h prior to sacrifice | AHR ko backcrossed to C57BL/6 |
| GSM254832 | i.p. 10 �g/kg TCDD 24h prior to sacrifice | C57BL/6 |
| GSM254844 | i.p. DMSO 24h prior to sacrifice | C57BL/6 |
| GSM254832 | i.p. 10 �g/kg TCDD 24h prior to sacrifice | C57BL/6 |
| GSM254844 | i.p. DMSO 24h prior to sacrifice | C57BL/6 |