Plugin: InParanoid Search

The Inparanoid program was developed at the Center for Genomics and Bioinformatics to address the need to identify orthologs. Homologs that originate from a speciation event are called orthologs and homologs that originate from a gene duplication event are called paralogs. If a duplication event predates the speciation event the parlogs are called outparalogs, and they can be present in different species. If instead an ortholog undegoes one or several duplication events, the resulting paralogs are called inparalogs, and they are co-orthologs to one or more orthologs in another species. Since an outparalog pair ought to have a more diversified function than inparalogs, it is useful to distinguish between the two. Furthermore, clustering inparalogs together allows proper identification of both one-to-one and many-to-many orthology cases. More in-depth information on this subject, the Inparanoid program and its applications has been previously published ( 1 ). The InParanoid program is available upon request to inparanoid@sbc.su.se

Species:

human, mouse, rat, fruitfly, nematode, zebrafish, thale-cress, frog, pig

URL Template:

http://inparanoid.sbc.su.se/cgi-bin/gene_search.cgi?id={{EnsemblGene}}&idtype=all&all_or_selection=all&specieslist=10&scorelimit=0.05&.submit=Submit+Query&.cgifields=specieslist&.cgifields=idtype&.cgifields=all_or_selection

Updated:

May 4, 2009

Registered:

May 4, 2009