{"rating_data": {"avg_stars": 0, "total": 0, "avg": 0}, "name": "Human Mast Cell Line", "created": "2024-05-30 07:26:00", "url": "https://www.creative-bioarray.com/filter/mast-cells-96.html", "lastmodified": "2024-05-30 07:26:00", "usage_data": {"layouts": 0.0, "users": 0}, "popularity": 0.0, "owner": {"username": "creativebioarray", "url": "/profile/21217/creativebioarray", "name": "Hannah Cole"}, "species": ["human", "mouse", "rat", "fruitfly", "nematode", "zebrafish", "thale-cress", "frog", "pig"], "shortUrl": "www.creative-bioarray.com", "id": 1372, "short_description": "Human Mast Cell Line", "role_permission": ["biogpsusers"], "permission_style": "public", "type": "iframe", "options": null, "tags": ["cell", "human", "line", "mast"], "description": " Mast cells are immune cells of the myeloid lineage and are present in connective tissues throughout the body. The activation and degranulation of mast cells significantly modulate many aspects of physiological and pathological conditions in a variety of settings. With respect to normal physiological functions, mast cells are known to regulate angiogenesis, vasodilation, vascular homeostasis, innate and adaptive immune responses. On the other hand, mast cells have also been implicated in the pathophysiology of many diseases, including allergy, asthma, gastrointestinal disorders, cardiovascular diseases and various malignancies.\n\n"}