000Zodiac2015-09-21 16:13:33http://compgenome.org/zodiac?Gene_List={{symbol}}2015-09-21 16:13:330.000.0cwu/profile/2/cwuChunlei Wuhumannematodecompgenome.org1194A comprehensive depiction of genetic interactions in cancer by integrating TCGA databiogpsuserspubliciframeNonecancergeneinteractiontcgaWe introduce Zodiac, a computational tool and resource to integrate existing knowledge about cancer genetic interactions with new information contained in TCGA data. It is an evolution of existing knowledge by treating it as a prior graph, integrating it with a likelihood model derived by Bayesian graphical model based on TCGA data, and producing a posterior graph as updated and data-enhanced knowledge. In short, Zodiac realizes "Prior interaction map + TCGA data → Posterior interaction map." Ref: http://www.ncbi.nlm.nih.gov/pubmed/25956356