{"rating_data": {"avg_stars": 0, "total": 0, "avg": 0}, "name": "Zodiac", "created": "2015-09-21 16:13:33", "url": "http://compgenome.org/zodiac?Gene_List={{symbol}}", "lastmodified": "2015-09-21 16:13:33", "usage_data": {"layouts": 0.0, "users": 0}, "popularity": 0.0, "owner": {"username": "cwu", "url": "/profile/2/cwu", "name": "Chunlei Wu"}, "species": ["human", "nematode"], "shortUrl": "compgenome.org", "id": 1194, "short_description": "A comprehensive depiction of genetic interactions in cancer by integrating TCGA data", "role_permission": ["biogpsusers"], "permission_style": "public", "type": "iframe", "options": null, "tags": ["cancer", "gene", "interaction", "tcga"], "description": "We introduce Zodiac, a computational tool and resource to integrate existing knowledge about cancer genetic interactions with new information contained in TCGA data. It is an evolution of existing knowledge by treating it as a prior graph, integrating it with a likelihood model derived by Bayesian graphical model based on TCGA data, and producing a posterior graph as updated and data-enhanced knowledge. In short, Zodiac realizes \"Prior interaction map + TCGA data \u2192 Posterior interaction map.\"\nRef: http://www.ncbi.nlm.nih.gov/pubmed/25956356"}