{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"sa1_Cre-ER-CTL_01": {"StrainOrLine": "E14_Cre-CTL"}}, {"sa1_Cre-ER-CTL_01": {"StrainOrLine": "E14_Cre-CTL"}}, {"sa1_Cre-ER-CTL_01": {"StrainOrLine": "E14_Cre-CTL"}}, {"sa1_Cre-ER-CTL_01": {"StrainOrLine": "E14_Cre-CTL"}}, {"sa1_Cre-ER-CTL_01": {"StrainOrLine": "E14_Cre-CTL"}}, {"sa1_Cre-ER-Tax_01": {"StrainOrLine": "E14_Cre-Tax"}}, {"sa1_Cre-ER-Tax_01": {"StrainOrLine": "E14_Cre-Tax"}}, {"sa1_Cre-ER-Tax_01": {"StrainOrLine": "E14_Cre-Tax"}}, {"sa1_Cre-ER-Tax_01": {"StrainOrLine": "E14_Cre-Tax"}}, {"sa1_Cre-ER-Tax_01": {"StrainOrLine": "E14_Cre-Tax"}}, {"sa1_STAT3-ER-CTL_01": {"StrainOrLine": "E14_STAT3-CTL"}}, {"sa1_STAT3-ER-CTL_01": {"StrainOrLine": "E14_STAT3-CTL"}}, {"sa1_STAT3-ER-CTL_01": {"StrainOrLine": "E14_STAT3-CTL"}}, {"sa1_STAT3-ER-CTL_01": {"StrainOrLine": "E14_STAT3-CTL"}}, {"sa1_STAT3-ER-LIF_01": {"StrainOrLine": "E14_STAT3-LIF"}}, {"sa1_STAT3-ER-LIF_01": {"StrainOrLine": "E14_STAT3-LIF"}}, {"sa1_STAT3-ER-LIF_01": {"StrainOrLine": "E14_STAT3-LIF"}}, {"sa1_STAT3-ER-LIF_01": {"StrainOrLine": "E14_STAT3-LIF"}}, {"sa1_STAT3-ER-LIF_01": {"StrainOrLine": "E14_STAT3-LIF"}}, {"sa1_STAT3-ER-Tax_01": {"StrainOrLine": "E14_STAT3-Tax"}}, {"sa1_STAT3-ER-Tax_01": {"StrainOrLine": "E14_STAT3-Tax"}}, {"sa1_STAT3-ER-Tax_01": {"StrainOrLine": "E14_STAT3-Tax"}}, {"sa1_STAT3-ER-Tax_01": {"StrainOrLine": "E14_STAT3-Tax"}}, {"sa1_STAT3-ER-Tax_01": {"StrainOrLine": "E14_STAT3-Tax"}}, {"sa1_STAT3-ER-Tax_01": {"StrainOrLine": "E14_STAT3-Tax"}}], "id": 8192, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "[u'This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th...", "geo_gse_id": "E-TABM-562", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 25, "tags": ["cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-mouse-embryonic-stem-14", "geo_id_plat": "E-TABM-562_A-AFFY-45", "name": "Transcription profiling of mouse embryonic stem cells to identify genes regulated by STAT3 and NANOG, known differentiation inhibitors", "created": "Nov.21, 2014", "summary": "[u'This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the European Union, ', {u'a': {u'href': u'http://www.fungenes.org', u'target': u'_blank', u'$': u'http://www.fungenes.org'}}, u'). The experiment was conducted at the Inst. National de la Sant\\xe9 et de la Recherche M\\xe9dicale - INS (INSERM U371, Bron, France) The goal of the experiment is to identify genes regulated by STAT3 and NANOG, which are known inhibitors of mouse ES cell differentiation.(I) E14-Cre-CTL cells deprived of LIF for 24 hours (n = 5);  (II) E14-Cre-Tax cells as in (I) and restimulated with 100 nM tamoxifen for 2 hours (n = 5); (III) E14-STATA3-CTL cells deprived of LIF and 4\\u2019OHT for 24 hours (n = 4); (IV) E14-STAT3-LIF cells treated as in (III) and re-stimulated with 10,000 U/ml LIF for 1 hour to reactivate endogenous  STAT3 (n = 5); (V) E14-STAT3-Tax cells as in (III) and restimulated with 100 nM 4\\u2019OHT for 2 hours to activate STAT3-ERT2 (n = 6);']", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-TABM-562", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-TABM-562/samples/"}