Dataset: Transcription profiling by array of bone marrow and peripheral blood samples from childhood leukemia patients
We examined published microarray data from 104 acute lymphoblastic leukaemia patient specimens, that represent six different subgroups...
We examined published microarray data from 104 acute lymphoblastic leukaemia patient specimens, that represent six different subgroups defined by cytogenetic features and immunophenotypes. Using the decision-tree based supervised learning algorithm Random Forest (RF), we determined a small set of genes for optimal subgroup distinction and subsequently validated their predictive power in an independent cohort of 68 specimens that were assessed using Affymetrix HG-U133A arrays.
- Species:
- human
- Samples:
- 68
- Source:
- E-TABM-125
- PubMed:
- 17002788
- Updated:
- Dec.12, 2014
- Registered:
- Jun.20, 2014
Factors:
(via ArrayExpress)
| Sample | CHROMOSOMAL ABNORMALITY | INDIVIDUAL | STRAIN | ORGANISM PART | CLINICAL HISTORY |
|---|---|---|---|---|---|
| T-ALL-7 | patient 14 | bone marrow | prognostic subgroup: T-ALL | ||
| MLL-2 | MLL | patient 86 | bone marrow | prognostic subgroup: MLL | |
| T-ALL-9 | patient 21 | bone marrow | prognostic subgroup: T-ALL | ||
| Hyperdip50-10 | Hyperdip50 | patient 59 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-22 | patient 94 | bone marrow | prognostic subgroup: T-ALL | ||
| T-ALL-24 | ALL-SIL | prognostic subgroup: T-ALL | |||
| T-ALL-4 | patient 6 | bone marrow | prognostic subgroup: T-ALL | ||
| Hyperdip50-2 | Hyperdip50 | patient 18 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-14 | patient 33 | bone marrow | prognostic subgroup: T-ALL | ||
| T-ALL-2 | patient 3 | bone marrow | prognostic subgroup: T-ALL | ||
| Hyperdip50-15 | Hyperdip50 | patient 74 | bone marrow | prognostic subgroup: Hyperdip50 | |
| Hyperdip50-4 | Hyperdip50 | patient 34 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-33 | PER-487 | prognostic subgroup: T-ALL | |||
| Hyperdip50-13 | Hyperdip50 | patient 68 | bone marrow | prognostic subgroup: Hyperdip50 | |
| Hyperdip50-11 | Hyperdip50 | patient 61 | bone marrow | prognostic subgroup: Hyperdip50 | |
| BCR-ABL-1 | BCR-ABL | patient 16 | bone marrow | prognostic subgroup: BCR-ABL | |
| MLL-3 | MLL | patient 88 | bone marrow | prognostic subgroup: MLL | |
| T-ALL-21 | patient 33 | peripheral blood | prognostic subgroup: T-ALL | ||
| Hyperdip50-1 | Hyperdip50 | patient 5 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-8 | patient 17 | bone marrow | prognostic subgroup: T-ALL | ||
| TEL-AML1-1 | TEL-AML1 | PER-608 | prognostic subgroup: TEL-AML1 | ||
| T-ALL-20 | patient 27 | peripheral blood | prognostic subgroup: T-ALL | ||
| E2A-PBX1-1 | E2A-PBX1 | patient 47 | bone marrow | prognostic subgroup: E2A-PBX1 | |
| E2A-PBX1-2 | E2A-PBX1 | PER-278 | prognostic subgroup: E2A-PBX1 | ||
| T-ALL-36 | PER-604 | prognostic subgroup: T-ALL | |||
| T-ALL-37 | PER-606 | prognostic subgroup: T-ALL | |||
| T-ALL-31 | PER-255 | prognostic subgroup: T-ALL | |||
| T-ALL-13 | patient 27 | bone marrow | prognostic subgroup: T-ALL | ||
| T-ALL-1 | patient 2 | bone marrow | prognostic subgroup: T-ALL | ||
| T-ALL-11 | patient 24 | bone marrow | prognostic subgroup: T-ALL | ||
| T-ALL-32 | PER-427 | prognostic subgroup: T-ALL | |||
| BCR-ABL-3 | BCR-ABL | patient 25 | bone marrow | prognostic subgroup: BCR-ABL | |
| T-ALL-16 | patient 71 | bone marrow | prognostic subgroup: T-ALL | ||
| T-ALL-6 | patient 11 | bone marrow | prognostic subgroup: T-ALL | ||
| Hyperdip50-12 | Hyperdip50 | patient 65 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-11 | patient 24 | bone marrow | prognostic subgroup: T-ALL | ||
| T-ALL-26 | DU528 | prognostic subgroup: T-ALL | |||
| Hyperdip50-14 | Hyperdip50 | patient 73 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-19 | patient 26 | bone marrow | prognostic subgroup: T-ALL | ||
| Hyperdip50-17 | Hyperdip50 | patient 76 | bone marrow | prognostic subgroup: Hyperdip50 | |
| Hyperdip50-7 | Hyperdip50 | patient 48 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-30 | PER-117 | prognostic subgroup: T-ALL | |||
| T-ALL-35 | PER-550 | prognostic subgroup: T-ALL | |||
| MLL-4 | MLL | patient 90 | bone marrow | prognostic subgroup: MLL | |
| Hyperdip50-5 | Hyperdip50 | patient 43 | bone marrow | prognostic subgroup: Hyperdip50 | |
| MLL-5 | MLL | PER-377 | prognostic subgroup: MLL | ||
| T-ALL-29 | MOLT4 | prognostic subgroup: T-ALL | |||
| Hyperdip50-8 | Hyperdip50 | patient 50 | bone marrow | prognostic subgroup: Hyperdip50 | |
| Hyperdip50-16 | Hyperdip50 | patient 75 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-5 | patient 10 | bone marrow | prognostic subgroup: T-ALL | ||
| MLL-7 | MLL | PER-490 | prognostic subgroup: MLL | ||
| Hyperdip50-3 | Hyperdip50 | patient 20 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-10 | patient 23 | bone marrow | prognostic subgroup: T-ALL | ||
| T-ALL-15 | patient 41 | bone marrow | prognostic subgroup: T-ALL | ||
| T-ALL-25 | CEM-CCRF | prognostic subgroup: T-ALL | |||
| T-ALL-23 | peripheral blood | prognostic subgroup: T-ALL | |||
| T-ALL-18 | patient 24 | peripheral blood | prognostic subgroup: T-ALL | ||
| T-ALL-19 | patient 26 | bone marrow | prognostic subgroup: T-ALL | ||
| MLL-1 | MLL | patient 9 | bone marrow | prognostic subgroup: MLL | |
| BCR-ABL-3 | BCR-ABL | patient 25 | bone marrow | prognostic subgroup: BCR-ABL | |
| T-ALL-34 | PER-537 | prognostic subgroup: T-ALL | |||
| Hyperdip50-6 | Hyperdip50 | patient 45 | bone marrow | prognostic subgroup: Hyperdip50 | |
| T-ALL-28 | Jurkat | prognostic subgroup: T-ALL | |||
| T-ALL-3 | patient 4 | bone marrow | prognostic subgroup: T-ALL | ||
| MLL-6 | MLL | PER-485 | prognostic subgroup: MLL | ||
| T-ALL-27 | HSB2 | prognostic subgroup: T-ALL | |||
| E2A-PBX1-3 | E2A-PBX1 | PER-371 | prognostic subgroup: E2A-PBX1 | ||
| Hyperdip50-9 | Hyperdip50 | patient 56 | bone marrow | prognostic subgroup: Hyperdip50 |