{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"CD34 cell A": {"CELL_TYPE": "CD34+ cell", "ORGANISM_PART": "bone marrow"}}, {"CD34 cell A": {"CELL_TYPE": "CD34+ cell", "ORGANISM_PART": "bone marrow"}}, {"T cell A": {"CELL_TYPE": "T cell", "ORGANISM_PART": "peripheral blood"}}, {"T cell A": {"CELL_TYPE": "T cell", "ORGANISM_PART": "peripheral blood"}}], "id": 1330, "ownerprofile_id": "arrayexpress_sid", "platform": 3, "summary_wrapped": "Expression profile comparison of peripheral blood lymphocytes (PBL) or haemopoietic stem cells (HSC) at the time of transduction with a...", "geo_gse_id": "E-MEXP-2983", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 4, "tags": ["cytokine", "leukemia", "peripheral"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-by-array-of-human-peripher", "geo_id_plat": "E-MEXP-2983_A-AFFY-33", "name": "Transcription profiling by array of human peripheral blood lymphocytes or haemopoietic stem cells at the time of transduction with a gammaretroviral vector", "created": "Jun.19, 2014", "summary": "Expression profile comparison of peripheral blood lymphocytes (PBL) or haemopoietic stem cells (HSC) at the time of transduction with a gammaretroviral vector. The analysis is performed in the context of two different gene therapy clinical trials  (Recchia et al, 2006; Aiuti et al, 2007) based on autologous infusion of human T cells or CD34+ haemopoietic progenitor cells gene-corrected with an moloney leukemia virus-derived vector (MLV-vector). T cells and CD34+ cells were isolated from patients and pre-stimulated in vitro with cytokines prior to transduction with the vector and re-infusion in patient. The expression profiles of T cells and CD34+ cells were analysed by microarray just after cytokine stimulation, providing information on the transcriptional activity of these two target cells at the time of transduction.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2983", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2983/samples/"}