ArrayExpress Uploader05170ALAALAALAC65SC65SC65SREFREFREFarrayexpress_sid4APE1/Ref-1 protects cells from oxidative stress by acting as a central enzyme in base excision repair pathways of DNA lesions and through...21865600E-MEXP-2941/profile/8773/arrayexpressuploader19centralDec.12, 2014Falsetranscription-profiling-by-array-of-human-hela-c-3E-MEXP-2941_A-AFFY-44Transcription profiling by array of human HeLa cell line wild type and mutations C65S and 31-34A to investigate how APE1/Ref-1 protects cells from oxidative stressSep.22, 2014APE1/Ref-1 protects cells from oxidative stress by acting as a central enzyme in base excision repair pathways of DNA lesions and through its independent activity as a redox transcriptional co-activator. To dissect between redox- and DNA-repair-mediated effects, here we performed transcription profiling of knock-in experiments using wild type and mutations C65S and 31-34A.http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2941humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2941/samples/