{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 5170, "factors": [{"ALA_1": {"GENOTYPE": "ALA"}}, {"ALA_1": {"GENOTYPE": "ALA"}}, {"ALA_1": {"GENOTYPE": "ALA"}}, {"C65S_1": {"GENOTYPE": "C65S"}}, {"C65S_1": {"GENOTYPE": "C65S"}}, {"C65S_1": {"GENOTYPE": "C65S"}}, {"REF_1": {"GENOTYPE": "REF"}}, {"REF_1": {"GENOTYPE": "REF"}}, {"REF_1": {"GENOTYPE": "REF"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "APE1/Ref-1 protects cells from oxidative stress by acting as a central enzyme in base excision repair pathways of DNA lesions and through...", "pubmed_id": 21865600, "geo_gse_id": "E-MEXP-2941", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 9, "tags": ["central"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-by-array-of-human-hela-c-3", "geo_id_plat": "E-MEXP-2941_A-AFFY-44", "name": "Transcription profiling by array of human HeLa cell line wild type and mutations C65S and 31-34A to investigate how APE1/Ref-1 protects cells from oxidative stress", "created": "Sep.22, 2014", "summary": "APE1/Ref-1 protects cells from oxidative stress by acting as a central enzyme in base excision repair pathways of DNA lesions and through its independent activity as a redox transcriptional co-activator. To dissect between redox- and DNA-repair-mediated effects, here we performed transcription profiling of knock-in experiments using wild type and mutations C65S and 31-34A.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2941", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2941/samples/"}