Dataset: The Co-inhibitory Receptor TIGIT has T cell intrinsic functions
We compared the gene expression in wild type CD4+ T cells stimulated with agonistic anti-TIGIT 4D4 antibody to that of isotype and TIGIT-...
We compared the gene expression in wild type CD4+ T cells stimulated with agonistic anti-TIGIT 4D4 antibody to that of isotype and TIGIT-deficient (KO) controls.
- Species:
- mouse
- Samples:
- 4
- Source:
- E-MEXP-2847
- PubMed:
- 21199897
- Updated:
- Dec.12, 2014
- Registered:
- Nov.21, 2014
Factors:
(via ArrayExpress)
| Sample | DOSE | STRAIN_OR_LINE | GENOTYPE | COMPOUND |
|---|---|---|---|---|
| B6_4D4 | 30 | C57BL/6-Tg(Tcra2D2,Tcrb2D2) | 2D2 mice | 4D4 antibody, TIGIT specific |
| B6_isotype | 30 | C57BL/6-Tg(Tcra2D2,Tcrb2D2) | 2D2 mice | Armenian hamster IgG isotype control (Biolegend) |
| TIGIT_KO_4D4 | 30 | C57BL/6 | TIGIT knock out | 4D4 antibody, TIGIT specific |
| TIGIT_KO_isotype | 30 | C57BL/6 | TIGIT knock out | Armenian hamster IgG isotype control (Biolegend) |