{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 8120, "factors": [{"D3_1": {"DOSE": 1000, "GENOTYPE": "wild_type", "COMPOUND": "leukemia inhibitory factor "}}, {"D3_1": {"DOSE": 1000, "GENOTYPE": "wild_type", "COMPOUND": "leukemia inhibitory factor "}}, {"D3_1": {"DOSE": 1000, "GENOTYPE": "wild_type", "COMPOUND": "leukemia inhibitory factor "}}, {"E-cad_1": {"DOSE": 1000, "GENOTYPE": "gene_knock_out", "COMPOUND": "leukemia inhibitory factor "}}, {"E-cad_1": {"DOSE": 1000, "GENOTYPE": "gene_knock_out", "COMPOUND": "leukemia inhibitory factor "}}, {"E-cad_1": {"DOSE": 1000, "GENOTYPE": "gene_knock_out", "COMPOUND": "leukemia inhibitory factor "}}, {"E-cad_LIFabsent_1": {"DOSE": 0, "GENOTYPE": "gene_knock_out", "COMPOUND": "untreated"}}, {"E-cad_LIFabsent_1": {"DOSE": 0, "GENOTYPE": "gene_knock_out", "COMPOUND": "untreated"}}, {"E-cad_LIFabsent_1": {"DOSE": 0, "GENOTYPE": "gene_knock_out", "COMPOUND": "untreated"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "We previously observed that E-cadherin knockout embryonic stem cells do not differentiate in the absence of the cytokine leukemia...", "pubmed_id": 21779327, "geo_gse_id": "E-MEXP-2836", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 3, "sample_count": 9, "tags": ["cadherin", "cytokine", "e-cadherin", "leukemia"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-by-array-of-mouse-wild-t-4", "geo_id_plat": "E-MEXP-2836_A-AFFY-45", "name": "Transcription profiling by array of mouse wild type and E-cadherin knockout embryonic stem cells grown with or without cytokine leukemia inhibitory factor", "created": "Nov.21, 2014", "summary": "We previously observed that E-cadherin knockout embryonic stem cells do not differentiate in the absence of the cytokine leukemia inhibitory factor (LIF) (Soncin et al., 2009, Stem Cells 27 p2069-2080). This experiment was designed to compare the transcription profile of E-cadherin KO ES cells cultured in the presence and absence of LIF. We also compared E-cadherin KO ES cells with wild type D3 ES cells grown in the presence of LIF.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2836", "species": "mouse", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2836/samples/"}