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Home › Dataset Library › Transcription profiling by array of mouse wild type and E-cadherin knockout embryonic stem cells grown with or without cytokine leukemia...

Dataset: Transcription profiling by array of mouse wild type and E-cadherin knockout embryonic stem cells grown with or without cytokine leukemia inhibitory factor

We previously observed that E-cadherin knockout embryonic stem cells do not differentiate in the absence of the cytokine leukemia...

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We previously observed that E-cadherin knockout embryonic stem cells do not differentiate in the absence of the cytokine leukemia inhibitory factor (LIF) (Soncin et al., 2009, Stem Cells 27 p2069-2080). This experiment was designed to compare the transcription profile of E-cadherin KO ES cells cultured in the presence and absence of LIF. We also compared E-cadherin KO ES cells with wild type D3 ES cells grown in the presence of LIF.

Species:
mouse

Samples:
9

Source:
E-MEXP-2836

PubMed:
21779327

Updated:
Dec.12, 2014

Registered:
Nov.21, 2014


Factors: (via ArrayExpress)
Sample DOSE GENOTYPE COMPOUND
D3_1 1000 wild_type leukemia inhibitory factor
D3_1 1000 wild_type leukemia inhibitory factor
D3_1 1000 wild_type leukemia inhibitory factor
E-cad_1 1000 gene_knock_out leukemia inhibitory factor
E-cad_1 1000 gene_knock_out leukemia inhibitory factor
E-cad_1 1000 gene_knock_out leukemia inhibitory factor
E-cad_LIFabsent_1 0 gene_knock_out untreated
E-cad_LIFabsent_1 0 gene_knock_out untreated
E-cad_LIFabsent_1 0 gene_knock_out untreated

Tags

  • cadherin
  • cytokine
  • e-cadherin
  • leukemia

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