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Home › Dataset Library › Transcription profiling by array of human HepG2 cells treated with TCDD

Dataset: Transcription profiling by array of human HepG2 cells treated with TCDD

[u'The integration of different \u201comics\u201d technologies has already been shown in several in vivo studies to offer a complementary...

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[u'The integration of different \u201comics\u201d technologies has already been shown in several in vivo studies to offer a complementary insight into cellular responses of toxic processes. We therefore hypothesize that the combining of transcriptomics and metabonomics data may improve the understanding of molecular mechanisms underlying non-genotoxic carcinogenicity in vitro. To test this hypothesis, the human hepatocarcinoma cell line HepG2 was exposed to the well known environmental pollutant TCDD. ', {u'br': None}, {u'br': None}, u'A custom CDF file is available on the FTP site for this experiment (in file E-MEXP-2817.additional.zip) for use with the normalized data file for this experiment.']

Species:
human

Samples:
18

Source:
E-MEXP-2817

PubMed:
21880148

Updated:
Dec.12, 2014

Registered:
Sep.22, 2014


Factors: (via ArrayExpress)
Sample DOSE TIME COMPOUND
12hour_DMSO_1 0.5 12 DMSO
12hour_DMSO_1 0.5 12 DMSO
12hour_DMSO_1 0.5 12 DMSO
12hour_TCDD_1 10.0 12 TCDD
12hour_TCDD_1 10.0 12 TCDD
12hour_TCDD_1 10.0 12 TCDD
24hour_DMSO_1 0.5 24 DMSO
24hour_DMSO_1 0.5 24 DMSO
24hour_DMSO_1 0.5 24 DMSO
24hour_TCDD_1 10.0 24 TCDD
24hour_TCDD_1 10.0 24 TCDD
24hour_TCDD_1 10.0 24 TCDD
48hour_DMSO_1 0.5 48 DMSO
48hour_DMSO_1 0.5 48 DMSO
48hour_DMSO_1 0.5 48 DMSO
48hour_TCDD_1 10.0 48 TCDD
48hour_TCDD_1 10.0 48 TCDD
48hour_TCDD_1 10.0 48 TCDD

Tags

  • cell
  • line

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