ArrayExpress Uploader0humannoneDONOR124 noneDONOR124 noneDONOR124 noneDONOR172 flucloxacillinDONOR124500flucloxacillinDONOR124500flucloxacillinDONOR124500flucloxacillinDONOR172500noneDONOR224 noneDONOR224 noneDONOR224 noneDONOR272 flucloxacillinDONOR224500flucloxacillinDONOR224500flucloxacillinDONOR224500flucloxacillinDONOR272500noneDONOR324 noneDONOR324 noneDONOR324 noneDONOR372 flucloxacillinDONOR324500flucloxacillinDONOR324500flucloxacillinDONOR324500flucloxacillinDONOR3725005136arrayexpress_sid4Drug-induced liver injury (DILI) due to flucloxacillin is a rare but serious complication of treatment with this antimicrobial. The...E-MEXP-2128/profile/8773/arrayexpressuploader424diseaseliverDec.12, 2014Falsetranscription-profiling-by-array-of-human-liver-afE-MEXP-2128_A-AFFY-44Transcription profiling by array of human liver after treatment with flucloxacillinSep.22, 2014Drug-induced liver injury (DILI) due to flucloxacillin is a rare but serious complication of treatment with this antimicrobial. The genetic basis of susceptibility is poorly understood as is the underlying molecular mechanism for disease. There is some evidence that flucloxacillin is a pregnane X receptor (PXR) agonist. The current study was concerned with investigating the relevance of PXR to flucloxacillin toxicity and with the identification of genes changing in expression in response to flucloxacillin.http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2128http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-2128/samples/