{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"Hnf1aHET1": {"genotype": "Hnf1a heterozygous mutant"}}, {"Hnf1aHET1": {"genotype": "Hnf1a heterozygous mutant"}}, {"Hnf1aHET1": {"genotype": "Hnf1a heterozygous mutant"}}, {"Hnf4a-pKO1": {"genotype": "pancreas-specific Hnf4alpha knockout"}}, {"Hnf4a-pKO1": {"genotype": "pancreas-specific Hnf4alpha knockout"}}, {"Hnf4a-pKO1": {"genotype": "pancreas-specific Hnf4alpha knockout"}}, {"Hnf4a-pKO-Hnf1aHET1": {"genotype": "Hnf4a-pKO;Hnf1aHET double mutant"}}, {"Hnf4a-pKO-Hnf1aHET1": {"genotype": "Hnf4a-pKO;Hnf1aHET double mutant"}}, {"Hnf4a-pKO-Hnf1aHET1": {"genotype": "Hnf4a-pKO;Hnf1aHET double mutant"}}, {"WT1": {"genotype": "wild type genotype"}}, {"WT1": {"genotype": "wild type genotype"}}, {"WT1": {"genotype": "wild type genotype"}}], "id": 8082, "pop_total": 0, "platform": 6, "summary_wrapped": "Gene expression differences between wild-type, pancreas-specific Hnf4alpha knockout (Hnf4a-pKO), heterozygous Hnf1alpha (Tcf1)...", "pubmed_id": 20523905, "geo_gse_id": "E-MEXP-1729", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 12, "tags": ["genome", "pancreas"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-by-array-of-pancreatic-i-2", "geo_id_plat": "E-MEXP-1729_A-AFFY-45", "name": "Transcription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice", "created": "Nov.21, 2014", "summary": "Gene expression differences between wild-type, pancreas-specific Hnf4alpha knockout (Hnf4a-pKO), heterozygous Hnf1alpha (Tcf1) (Hnf1aHET), and double mutant (Hnf4a-pKO;Hnf1aHET) mouse pancreatic islets were assesed using amplified RNA samples from islets of matched quality and endocrine purity, obtained from 60-75 day-old control and genetically modified male mice after 48 hours in culture. RNA was amplified using the Affymetrix GeneChIP two-cycle protocol and hybridized to Affymetrix GeneChip Mouse Genome 430 2.0 arrays [Mouse430_2].", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-1729", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-1729/samples/"}