Dataset: Transcription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice

Gene expression differences between wild-type, pancreas-specific Hnf4alpha knockout (Hnf4a-pKO), heterozygous Hnf1alpha (Tcf1) (Hnf1aHET), and double mutant (Hnf4a-pKO;Hnf1aHET) mouse pancreatic islets were assesed using amplified RNA samples from islets of matched quality and endocrine purity, obtained from 60-75 day-old control and genetically modified male mice after 48 hours in culture. RNA was amplified using the Affymetrix GeneChIP two-cycle protocol and hybridized to Affymetrix GeneChip Mouse Genome 430 2.0 arrays [Mouse430_2].

Species:

mouse

Samples:

12

Source:

E-MEXP-1729

PubMed:

20523905

Updated:

Dec.12, 2014

Registered:

Nov.21, 2014