ArrayExpress Uploaderarrayexpress_sid9538infected37cerebral cortex624infected37hippocampus624infected37cerebral cortex624infected37hippocampus624infected37cerebral cortex624infected37hippocampus624infected21cerebral cortex240infected21hippocampus240infected21cerebral cortex240infected21hippocampus240infected21cerebral cortex240infected21hippocampus240reference12cerebral cortex24reference12hippocampus24reference12cerebral cortex24reference12hippocampus24reference12cerebral cortex24reference12hippocampus24reference14cerebral cortex72reference12hippocampus72reference14cerebral cortex72reference14hippocampus72reference14cerebral cortex72reference14hippocampus72infected14cerebral cortex72infected14hippocampus72infected12cerebral cortex24infected12hippocampus24infected12cerebral cortex24infected12hippocampus24infected12cerebral cortex24infected12hippocampus24infected14cerebral cortex72infected14hippocampus72infected14cerebral cortex72infected14hippocampus72reference21cerebral cortex240reference21hippocampus240reference12cerebral cortex240reference21hippocampus240reference21cerebral cortex240reference21hippocampus240reference37cerebral cortex624reference37hippocampus624reference37cerebral cortex624reference37hippocampus624reference37cerebral cortex624reference37hippocampus624011[u'The aim of this work is to describe the transcriptomic changes underlying the complex mechanisms of the host response to pneumococcal...20565785E-MEXP-1656/profile/8773/arrayexpressuploader448bacterial meningitisbraincortexdiseasehippocampusmeningitispneumococcal meningitisFeb.09, 2015FalseE-MEXP-1656_A-AFFY-43transcription-profiling-of-rat-hippocampus-and-corTranscription profiling of rat hippocampus and cortex in the time series of Pneumococcal Meningitis infectionJan.12, 2015[u'The aim of this work is to describe the transcriptomic changes underlying the complex mechanisms of the host response to pneumococcal meningitis in a temporal and spatial context. For this purpose we evaluated the gene expression profile of the two brain structures predominantly affected by brain damage i.e. the cortex and the hippocampus at four different stages of the disease (24-, 72-, 240- and 624 hours post infection) using an infant rat model. ', {u'br': None}, {u'br': None}, u'The first two timepoints represent the acute and late disease phase of bacterial meningitis (BM) and 10 and 26days the recovery phase. At each timepoint 6 infected and 6 sham infected animals were sacrificed. Control and infected animals were age matched to avoid differences in the gene expression patterns due to developmental processes in the infant rat brain.']http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-1656rathttp://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-1656/samples/