{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 5100, "factors": [{"SAMPLEAPE1B1": {"RNA interference": "APE1 RNAi"}}, {"SAMPLEAPE1B1": {"RNA interference": "APE1 RNAi"}}, {"SAMPLEAPE1B1": {"RNA interference": "APE1 RNAi"}}, {"SAMPLECntlA1": {"RNA interference": "scrambled control"}}, {"SAMPLECntlA1": {"RNA interference": "scrambled control"}}, {"SAMPLECntlA1": {"RNA interference": "scrambled control"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Transcriptional profiling was done following APE1/Ref1 silencing using conditional gene expression knockdown by RNA interference (RNAi)...", "pubmed_id": 19180539, "geo_gse_id": "E-MEXP-1315", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "rnai-knock-down-of-the-dna-repair-enzyme-and-trans", "geo_id_plat": "E-MEXP-1315_A-AFFY-44", "name": "RNAi knock down of the DNA-repair enzyme and transcriptional co-activator APE1 in human HeLa cells", "created": "Sep.22, 2014", "summary": "Transcriptional profiling was done following APE1/Ref1 silencing using conditional gene expression knockdown by RNA interference (RNAi) technology in HeLa cell lines. APE1 is a DNA-repair enzyme and transcriptional co-activator. Knockdown leads to cell-growth arrest, apoptosis and impairment in the intracellular redox state and cytoskeletal perturbation.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-1315", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-1315/samples/"}