{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM244277": {"STRAIN/GENOTYPE": "C57/BL6 (wild type)", "BIOSOURCEPROVIDER": "David Gattas"}}, {"GSM244277": {"STRAIN/GENOTYPE": "C57/BL6 (wild type)", "BIOSOURCEPROVIDER": "David Gattas"}}, {"GSM244277": {"STRAIN/GENOTYPE": "C57/BL6 (wild type)", "BIOSOURCEPROVIDER": "David Gattas"}}, {"GSM244277": {"STRAIN/GENOTYPE": "C57/BL6 (wild type)", "BIOSOURCEPROVIDER": "David Gattas"}}, {"GSM244277": {"STRAIN/GENOTYPE": "C57/BL6 (wild type)", "BIOSOURCEPROVIDER": "David Gattas"}}, {"GSM244277": {"STRAIN/GENOTYPE": "C57/BL6 (wild type)", "BIOSOURCEPROVIDER": "David Gattas"}}, {"GSM244277": {"STRAIN/GENOTYPE": "C57/BL6 (wild type)", "BIOSOURCEPROVIDER": "David Gattas"}}, {"GSM244277": {"STRAIN/GENOTYPE": "C57/BL6 (wild type)", "BIOSOURCEPROVIDER": "David Gattas"}}, {"GSM244277": {"STRAIN/GENOTYPE": "C57/BL6 (wild type)", "BIOSOURCEPROVIDER": "David Gattas"}}], "id": 8307, "ownerprofile_id": "arrayexpress_sid", "platform": 7, "summary_wrapped": "To describe the transcriptional changes associated with polymicrobial-sepsis induced myocardial depression in wild type and iNOS...", "geo_gse_id": "E-GEOD-9667", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 9, "tags": ["aorta", "artery", "common carotid artery", "heart", "left", "left ventricle", "myocardium", "right", "right common carotid artery", "ventricle"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "polymicrobial-sepsis-induced-myocardial-depression", "geo_id_plat": "E-GEOD-9667_A-AFFY-23", "name": "Polymicrobial sepsis-induced Myocardial Depression Transcriptional Profile", "created": "Nov.23, 2014", "summary": "To describe the transcriptional changes associated with polymicrobial-sepsis induced myocardial depression in wild type and iNOS deficient mice. Keywords: myocardium, contractility, differential gene expression, nitric oxide synthase, infection We compared the transcriptional profile of C57/BL6 WT mice and congenic B6 129P2-Nos2tm1Lau/J mice after 48 hrs of polymicrobial sepsis induced by caecal ligation and perforation. 48 hours after surgery, mice were anaesthetised (intraperitoneal 100 mg/kg ketamine and 10 mg/kg xylazine). The right common carotid artery was cannulated (Millar Mikro-Tip pressure transducing catheter: 1.4F sensor, 2F catheter; Houston TX). Pressure tracings from the aorta and left ventricle were recorded (SonoLAB software; Sonometrics Corp., London Ontario Canada) and analysed using Cardiosoft and Origin 6.0 (Sonometrics Corp., and Microcal Software, Northampton MA). The heart was removed, emptied of blood, and snap frozen.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-9667", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-9667/samples/"}