{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSE9656GSM243838": {}}, {"GSE9656GSM243839": {}}, {"GSE9656GSM243840": {}}, {"GSE9656GSM243841": {}}, {"GSE9656GSM243842": {}}, {"GSE9656GSM243843": {}}, {"GSE9656GSM243844": {}}, {"GSE9656GSM243845": {}}, {"GSE9656GSM243846": {}}, {"GSE9656GSM243847": {}}, {"GSE9656GSM243848": {}}, {"GSE9656GSM243849": {}}, {"GSE9656GSM243850": {}}, {"GSE9656GSM243851": {}}, {"GSE9656GSM243852": {}}, {"GSE9656GSM243853": {}}, {"GSE9656GSM243854": {}}, {"GSE9656GSM243855": {}}, {"GSE9656GSM243856": {}}, {"GSE9656GSM243857": {}}, {"GSE9656GSM243858": {}}, {"GSE9656GSM243859": {}}, {"GSE9656GSM243860": {}}, {"GSE9656GSM243861": {}}, {"GSE9656GSM243862": {}}, {"GSE9656GSM243863": {}}, {"GSE9656GSM243864": {}}, {"GSE9656GSM243865": {}}, {"GSE9656GSM243866": {}}, {"GSE9656GSM243867": {}}, {"GSE9656GSM243868": {}}, {"GSE9656GSM243869": {}}, {"GSE9656GSM243870": {}}, {"GSE9656GSM243871": {}}, {"GSE9656GSM243872": {}}, {"GSE9656GSM243873": {}}, {"GSE9656GSM243874": {}}], "id": 5052, "pop_total": 0, "platform": 4, "summary_wrapped": "Waldenstr\u00f6ms macroglobulinemia (WM) is a rare lymphoproliferative disorder with apparent morphologic and immunophenotypic heterogeneity...", "geo_gse_id": "E-GEOD-9656", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 37, "tags": ["bone", "bone marrow", "macroglobulinemia", "peripheral", "tonsil"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-human-waldenstroms-macr", "geo_id_plat": "E-GEOD-9656_A-AFFY-44", "name": "Transcription profiling of human Waldenstroms macroglobulinemia CD19+ WM B cells (WM-BC) and CD138+ WM plasma cells (WM-PC) with those of normal CD19+ peripheral blood B cells (PB-BC), tonsil-BC (T-BC), CD138+ T-PC and bone marrow PC (N-PC) reveals biological insights into its pathophysiology", "created": "Sep.22, 2014", "summary": "Waldenstr\u00f6ms macroglobulinemia (WM) is a rare lymphoproliferative disorder with apparent morphologic and immunophenotypic heterogeneity and its origins are still poorly understood. In this study, using Gene-Expression Profiling (GEP), we compared the global mRNA expression patterns of CD19+ WM B cells (WM-BC) and CD138+ WM plasma cells (WM-PC) with those of normal CD19+ peripheral blood B cells (PB-BC), tonsil-BC (T-BC), CD138+ T-PC and bone marrow PC (N-PC). Experiment Overall Design: The sample cohort studied consisted of CD19-selected peripheral blood B cells (PB-BC; n = 7), tonsil B cells (T-BC; n = 7), bone marrow B cells from WM (WM-BC; n = 12), tonsil plasma cells (T-PC; n = 9), bone marrow plasma cells from healthy donors (N-PC; n = 10), WM plasma cells (WM-PC, n = 9), and MM plasma cells (MM-PC; n = 11).", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-9656", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-9656/samples/"}