ArrayExpress Uploaderarrayexpress_sidhumannot specifiedTX40AR IAnot specifiednot specifiednot specifiedHôpital Bicêtre, Paris, Francenot specifiednot specifiednot specifiedTX22AR IAnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX01AR IAnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX25AR IBnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX03AR IBnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX25AR IBnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX11AR IIAnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX50AR IIBnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX53AR+CANnot specifieddeceasednot specifiedHôpital 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Tenon, Paris, Francenot specifiednot specifiednot specifiedTX29CAN IIInot specifiedlivingnot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX07CAN IIInot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX26CAN IIInot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX04CAN IIInot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX32CAN IIInot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX49non-rejectingnot specifieddeceasednot specifiedHôpital Pellegrin, Bordeaux, Francenot specifiednot specifiednot specifiedTX21non-rejectingnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX12non-rejectingnot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX08non-rejectingnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX25non-rejectingnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedTX37non-rejectingnot specifiedlivingnot specifiedHôpital Bicêtre, Paris, Francenot specifiednot specifiednot specifiedTX27non-rejectingnot specifiedlivingnot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC01not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC03not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC04not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC05not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC06not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC06not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC10not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC11not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC11not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC13not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC14not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC15not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiedC16not specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specified1-MECAN Inot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specified3-AOCAN Inot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specified4-MSCAN Inot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specified70-PJnon-rejectingnot specifieddeceasednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specified281004-L7, Control kidney sample from nephrectomynot specifiednot specifiednot specifiednot specifiedHôpital Tenon, Paris, Francenot specifiednot specifiednot specifiednot specifiednot specifiednot specifiednot specifiednot specifiedAMS Biotechnology, Abingdon, UKnot specifiednot specified53not specifiednot specified107 microMol/Lnot specifiedZ01not specifiedfemalenon-rejecting52not specifiednot specifiedn.d. Renal graft bx: Z02not specifiednot specifiednot specifiedfemalenon-rejecting47not specifiednot specified94 microMol/Lnot specifiedZ05not specifiedmaleborderline changes53not specifiednot specified167 microMol/Lnot specifiedZ06not specifiedmalenon-rejecting53not specifiednot specified163 microMol/Lnot specifiedZ07not specifiedmaleAR IB, IIA45not specifiednot specified95 microMol/Lnot specifiedZ10not specifiedmalenon-rejecting45not specifiednot specified106 microMol/Lnot specifiedZ11not specifiedmalenon-rejecting30not specifiednot specified159 microMol/Lnot specifiedZ13not specifiedmalenon-rejecting64not specifiednot specified115 microMol/Lnot specifiedZ14not specifiedfemalenon-rejecting64not specifiednot specified114 microMol/Lnot specifiedZ15not specifiedfemalenon-rejecting53not specifiednot specified117 microMol/Lnot specifiedZ16not specifiedmalenon-rejecting29not specifiednot specified152 microMol/Lnot specifiedZ17not specifiedmalenon-rejecting29not specifiednot specified108 microMol/Lnot specifiedZ18not specifiedmalenon-rejecting59not specifiednot specified144 microMol/Lnot specifiedZ19not specifiedmaleAR IIA52not specifiednot specifiedn.d. microMol/Lnot specifiedZ20not specifiedfemalenon-rejecting30not specifiednot specified94 microMol/Lnot specifiedZ21not specifiedfemalenon-rejecting503904This SuperSeries is composed of the following subset Series: GSE9489: Analyses of heterogeneous renal allograft biopsies reveal conserved.../profile/8773/arrayexpressuploader982proteinDec.12, 2014FalseE-GEOD-9493_A-AFFY-44transcriptomic-analyses-of-renal-allograft-biopsiehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-9493Transcriptomic analyses of renal allograft biopsies reveal conserved rejection signatures and molecular pathwaysSep.22, 2014This SuperSeries is composed of the following subset Series: GSE9489: Analyses of heterogeneous renal allograft biopsies reveal conserved rejection signatures and molecular pathways I GSE9492: Analyses of heterogeneous renal allograft biopsies reveal conserved rejection signatures and molecular pathways II GSE17861: Analyses of heterogeneous renal allograft biopsies reveal conserved rejection signatures and molecular pathways I, partB Publication of acute rejection signature: Saint-Mezard P, Berthier CC, Zhang H, Hertig A, Kaiser S, Schumacher M, Wieczorek G, Bigaud M, Kehren J, Rondeau E, Raulf F, Marti HP. Analysis of independent microarray datasets of renal biopsies identifies a robust transcript signature of acute allograft rejection. Transpl. Int. 2009 Mar;22(3):293-302. Epub 2008 Nov 6. PMID: 19017305. We characterized a common transcriptional profile of 70 genes, defined as acute rejection transcript set (ARTS). ARTS expression is significantly up-regulated in all AR samples as compared with stable allografts or healthy kidneys, and strongly correlates with the severity of Banff AR types. Publication of metzincins expression signature in IF/TA (CAN): Rödder S, Scherer A, Raulf F, Berthier CC, Hertig A, Couzi L, Durrbach A, Rondeau E, Marti HP. Renal allografts with IF/TA display distinct expression profiles of metzincins and related genes. Am. J. Transplant. 2009 Mar;9(3):517-526. Epub 2009 Feb 3. PMID: 19191772. As members of the protease family metzincins and functionally related genes are involved in fibrotic and sclerotic processes of the extracellular matrix (ECM), we hypothesized their deregulation in IF/TA. Gene expression and protein level analyses using allograft biopsies with and without Banff'05 classified IF/TA illustrated their deregulation. Expression profiles of these genes differentiated IF/TA from Banff'05 classified Normal biopsies in three independent microarray studies and demonstrated histological progression of IF/TA I to III. Keywords: SuperSeries Refer to individual SeriesE-GEOD-9493http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-9493/samples/