ArrayExpress Uploaderarrayexpress_sid789106We compared gene expression profiles of lymphotoxin alpha- and lymphtoxin beta receptor-deficient thymic medullary epithelial cells with...17947641E-GEOD-8563/profile/8773/arrayexpressuploader018Dec.12, 2014FalseE-GEOD-8563_A-AFFY-45transcription-profiling-of-mouse-lymphtoxin-beta-rTranscription profiling of mouse lymphtoxin beta receptor-deficient thymic medullary epithelial cells vs. wild-type and Aire-deficient vs wild-type littermatesNov.18, 2014We compared gene expression profiles of lymphotoxin alpha- and lymphtoxin beta receptor-deficient thymic medullary epithelial cells with their wild-type littermates, as well as with Aire-deficient and wild-type littermates. This was done in order to determine whether there was overlap in the effects of lymphotoxin and aire. Experiment Overall Design: Individual thymi were digested with collagenase, dispase and DNAse, and meduallary epithelial cells with the phenotype CD45-G8.8+Ly51intMHCclasssIIhi were isolated by FACS.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-8563mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-8563/samples/